Evonik Degussa Gmbh

Degussa Aktiengesellschaft

Oxeno Olefinchemie Gmbh

Evonik Oxeno Gmbh

Ratiopharm Gmbh

Basf Se Corporation

Armin Boerner

Detlef Selent

Dieter Hess

Robert Franke

Jens Holz

Klaus-Diether Wiese

Renat Kadyrov

Dirk Fridag

Katrin Marie Dyballa

Thomas Riermeier

Karlheinz Drauz

Uwe Dingerdissen

Cornelia Borgmann

Axel Monsees

Burkard Kreidler

Vitali Tararov

Dirk Roettger

Gerd Koenig

Andrei Korostylev

Carsten A Schneider

Wilfried Bueschken

Hans-Peter Krimmer

Andrea Christiansen

Marc Becker

Dagmara Ortmann

Juan Jose Almena Perea

Oliver Moeller

Jiri Stohandl

Jaroslav Frantisek

Karl-Josef Haack

Jutta Lang

Detlef Heller

Katharina Rumpel

Pavel Bobal

Kane Denike

Nicolas Jeker

Odalys Esperanza Zayas Vargas

The present invention relates to chiral compounds with two optically active phosphorus atoms, chiral transition metal catalysts which comprise these compounds as ligands, a process for preparing the P-chiral compounds and processes for asymmetric synthesis using the chiral transition metal catalysts. The present invention specifically relates to a process for preparing an optically active carbonyl compound by asymmetric hydrogenation of a prochiral &#x3b1;,&#x3b2;-unsaturated carbonyl compound with hydrogen in the presence of an optically active transition metal catalyst according to the invention. Yet more specifically, the present invention relates to a process for the asymmetric hydrogenation of citral, and also a process for preparing optically active menthol.

P-chiral phosphine ligands and use thereof for asymmetric synthesis

Disclosed herein are compounds of formula (I): 

Bisphosphites having an unsymmetric outer biphenol unit

Bisphosphites having at least one unsymmetric outer biphenol unit are useful for the hydroformylation of an olefin.

Bisphosphites having an outer naphthyl-phenyl unit and a central 2,3'-biphenol unit and their preparation are described.

Bisphosphites having an outer naphthyl-phenyl unit and a central 2,3'-biphenol unit

Bisphosphites having an outer naphthyl-phenyl unit.

Bisphosphites having an outer naphthyl-phenyl unit

The subject matter of the present invention is a plurality of products and the use thereof as a catalytically active composition in a method for producing aldehydes.

Organophosphorus compounds based on anthracenetriol

The invention relates to a method for separating 1-butene from C-containing hydrocarbon mixtures, comprising isobutene and 1-butene, by hydroformylation, wherein the catalytic system used is made of one of the transition metals of the group 8 to 10, preferably rhodium, and a bisphosphite ligand of the formula (I), where X is a divalent substituted or unsubstituted bisalkylene or bisarylene group having one or more heteroatom(s), Y is a divalent substituted or unsubstituted bisarylene or bisalkylene group having one or more heteroatom(s), Z is oxygen or NR, and R, R, R, Rare identical or different, substituted or unsubstituted, linked, unlinked or condensed aryl or heteroaryl groups, and Ris hydrogen or a substituted or unsubstituted alkyl or aryl group having one or more heteroatom(s), wherein the bisphosphite ligand of the formula (I) is used in an excess of a molar ratio of 100:1 to 1:1 to the transition metal, and that with a 1-butene conversion of more than 95% less than 5% of the present isobutene is reacted method for separating 1-butene from c-containing hydrocarbon streams by hydroformylation.

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The invention relates to a device and a method for the continuous reaction of a liquid and a second fluid, wherein the device comprises at least two jet loop reactors interconnected in parallel and common outer liquid recirculation.

Parallelized jet loop reactors

The present invention relates to a process for the production of statins, which are known as HMG-CoA reductase inhibitors. A few of the intermediate compounds for use in the process in accordance with the invention are novel compounds and the invention also relates to these novel intermediate compounds.

Method for the production of statins

The invention relates to a bisphosphite of the formula I where X=a divalent substituted or unsubstituted bisalkylene or bisarylene radical, Y=a divalent substituted or unsubstituted bisarylene or bisalkylene radical, Z=oxygen or NR, and R, R, R, Rare identical or different, substituted or unsubstituted, linked, unlinked or fused aryl or heteroaryl radicals and Ris hydrogen or a substituted or unsubstituted alkyl or aryl radical, a process for preparing it and also the use of this phosphite in catalysis in particular in the catalytic hydroformylation of olefins or organic compounds having C&#x2014;C double bonds.

Bisphosphite ligands for hydroformylation catalyzed by transition metals

The present invention relates to a process for preparing pyrrole derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, and more particularly to improved synthetic methods for preparing 3,5-dihydroxy-7-pyrrol-1-yl heptanoic acids from 1,4-diketo starting materials. The invention further relates to intermediates in this process formula (I). 

Process for preparing pyrrole derivatives and intermediates

The present invention is based on new ligand systems of the general formula (I). These ligand systems can be used advantageously in transition metal-catalyzed asymmetric syntheses. Likewise encompassed are the transition metal complexes thus prepared, a process for preparing the ligands and the use of the complexes in asymmetric synthesis. 

Unsymmetrically substituted phospholane catalysts

The present invention relates to ligands of the general formula (I). In addition, a process for the production thereof and the use thereof are demonstrated.

Bisphosphines as bidentate ligands

(EN) The invention relates to the use of novel organophosphoric compounds and metal complexes thereof in catalytic reactions, and to the hydroformylation of olefins in the presence of these compounds.

Method for hydroformylating olefins in the presence of organophosphoric compounds

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Rostock, Germany

Armin Boerner