Adir Et Compagnie

Armel Fradin

Jacqueline Bonnet

Guillaume De Nanteuil

Jean-Daniel Brion

Yves Rolland

Luc Demuynck

Lucy De Montarby

Pietro Ghezzi

Anne-Marie Chollet

Michel Vincent

Bernard Portevin

Christine Lila

A compound of formula (I): ##STR1## wherein: R.sub.1 represents halogen or a different group as defined in the description,

Benzimidazole, benzoxazole and benzothiazole compounds

A compound of formula (I): ##STR1## in which: R.sub.1 represents halogen or hydroxyl, alkoxy, trihalomethyl, amino, mercapto, alkylthio, trialkylammonium, aryloxy, arylthio, arylsulfonyl, arylsulfonyloxy, cycloalkyloxy, cycloalkylthio, bicycloalkyloxy or bicycloalkylthio,

A compound of formula (I): ##STR1## in which X, n, B and Y are as defined in the description. useful as cytokine inhibitors.

Heterocyclic compounds

New benzothiazine derivatives corresponding to the general formula I: ##STR1## in which: X represents halogen,

Phenothiazine cytokine inhibitors

Compound of formula (I): ##STR1## in which: R.sub.1 represents 1-adamantyl, dicyclopropylmethyl, substituted or unsubstituted (C.sub.3 -C.sub.6) cycloalkyl or substituted or unsubstituted bicyclo[2.2.2]oct-1-yl,

4-methyl-5-substituted-1,3-oxazoles having anti-inflammatory activity

Compound of formula (I): ##STR1## in which: R.sub.1 represents halogen, or hydroxy, alkyl, alkoxy, cyano, amino, mercapto, alkylthio or phenoxy,

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Neuilly sur Seine, France

Armel Fradin