Universidad Nacional Autónoma De México

Armando Perez Torres

Karen Manucharyan

René Alvaro Segura Velázquez

Gladis Del Carmen Fragoso Gonzalez

Jacquelynne Brenda Cervantes Torres

Edda Lydia Sciutto Conde

Victor Guadalupe García Gonzalez

Jaime Mas Oliva

Diana Torres Garcia

Blanca Alicia Delgado Coello

Víctor Guadalupe GARCÍA Gonzalez

The present invention refers to the use of the peptide defined by the amino acid sequence G-Y-Y-Y-P-S-D-P-N-T-F-Y-A-P-P-Y-S-A, named GK-1, to be used as an antitumor and antimetastatic agent or for the treatment of cancer, specifically of basal cell carcinoma, squamous cell carcinoma, transitional cell carcinoma, and adenocarcinoma, and preferably for the treatment of breast cancer.

Use of the GK-1 peptide as an antitumoral and/or antimetastatic agent

The present invention provides a novel vaccine compound of micellar nanoparticles to be administered intranasally to treat and/or prevent the disease called atherosclerosis, which results from an abnormal metabolism of circulating lipids. The novelty of the vaccine compound of the present invention is the use of Archaebacterian lipids, lysophosphatidylcholine, and phosphatidylcholine, which give nanoparticles stability and facilitates antigen presentation in its appropriate secondary peptidic conformation. A novel process for the preparation of vaccine compounds which allows obtaining homogeneous nanoparticles with high stability is also presented in this invention.

Nasal vaccine against the development of atherosclerosis disease and fatty liver

Growing community of inventors

Mexico City, Mexico

Armando Perez Torres