Aventis Pharma S.a.

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Laurent Schio

Olivier Courtin

Dominique Melon Manguer

The invention concerns compounds of general formula (I) wherein: Rrepresents a hydrogen atom, a hydroxy radical, Ob or Ncd; A represents an oxygen atom, a CHradical or a NH radical; B represents the radical of a steroid; Rrepresents a hydrogen atom, a methyl or hydroxyl radical; Rrepresents a hydrogen atom or a hydroxyl radical; T represents a hydrogen atom, a methyl radical, a CHCONH, CHC&#x2261;N radical, a (CH)NHor (CH)2NalkXradical; X being a halogen atom and alc an alkyl radical; Y represents a hydrogen atom, a hydroxyl radical or a halogen atom or a OSOH radical; W represents a hydrogen atom or a OH radical; Z represents a hydrogen atom or a methyl radical. The compounds of formula (I) exhibit antifungal properties.

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Romainville, France

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