Banner Pharmacaps, Inc.

Aristippos Gennadios

Roger E Gordon

Don A Archibald

Linus G Fonkwe

Michelle A Gillette

A film-forming hydrocolloid composition comprising kappa carrageenan, iota carrageenan, a bulking agent, plasticizer and water is described. The ratio of bulking agent to total carrageenan is from about 1:1 to 20:1. Kappa carrageenan is present in an amount of less than or equal to 50% by weight of total carrageenan present. To form the composition, all dry materials are mixed and added to a heated mixture of all liquid materials. The final mixture is heated until a composition free of particulate materials is formed. The formed composition can be cast or extruded into ribbons, films, sheets, tubes or the like, for encapsulating wet or dry materials including medicinal dosage forms, nutritional supplements, cosmetics, bath oils and gels, and paint balls.

Non-gelatin capsule shell formulation

The present invention is a process for coloring gelatin-based formulations involving adding a saturated fatty acid to the gelatin-based formulation along with lake pigment, whereby the saturated fatty acid is added in an amount so as to prevent cross-linking between the gelatin-based formulations and the aluminum cations released by the lake pigments. Preferably, this amount is about 10% to about 300% by weight of the added lake pigment content. With this process, the resulting colored gelatin exhibits acceptable machineability characteristics and disintegration. As an example, the colored gelatin produced by this process has a viscosity of less than approximately 10,000 cP at about 60&deg; C. Additionally, the present invention is a gelatin-based formulation made from the above-described process. The gelatin-based formulation includes gelatin, lake pigment(s), and a sufficient amount of fatty acid to prevent cross-linking between the gelatin and the cations released from the lake pigment(s). Further, the present invention includes a dosage form that includes the described gelatin-based formulation as the sheath material. The dosage form may encapsulate a liquid, suspension, semi-solid, or solid pharmaceutical, nutritional, herbal, or personal care product, or combination thereof.

Colored gelatin-based formulations and method

Non-gelatin substitutes for oral delivery capsules, their composition and process of manufacture

Gum acacia substituted soft gelatin capsules

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Greensboro, NC, United States of America

Aristippos Gennadios