National University of Singapore

Other

Arijit Biswas

Chui Yee Fong

Mahesh Choolani

Tuan Ariffeen Bongso

Seeram Ramakrishna

Khalil Razvi B M Jabarullah Khan

Loganath Annamalai

Changqing Zhao

Mahesh Arjandas Choolani

The invention is directed to a method of treating a wound (e.g., to suppress scar formation) in an individual in need thereof comprising contacting the wound with an effective amount of a composition comprising (i) Wharton's jelly stem cells (WJSCs), (ii) a cell culture medium that has been conditioned with WJSCs, (iii) a lysate of WJSCs, (iv) a cell culture medium that has been conditioned with WJSCs exposed to apoptotic skin cells and keloid cells, or (v) a combination thereof. The invention is directed to a medical dressing (e.g., pharmaceutical compositions) comprising Wharton's jelly stem cells (WJSCs), a cell culture medium that has been conditioned with WJSCs, a lysate of WJSCs, a cell culture medium that has been conditioned with WJSCs exposed to apoptotic skin cells and keloid cells, or a combination thereof.

Wound dressing nanomesh impregnated with human umbilical cord Wharton's jelly stem cells

In one aspect, the invention is directed to methods of expanding hematopoietic stem cells (HSCs) comprising culturing the HSCs with Wharton's Jelly mesenchymal stem cells (WJSCs), a cell culture medium that has been conditioned with WJSCs, or a combination thereof, thereby producing a HSC culture; and maintaining the HSC culture under conditions in which the HSCs expand in the culture, thereby expanding the HSCs. In another aspect, the invention is directed to a method of transplanting the expanded HSCs in an individual in need thereof. In yet another aspect, the invention is directed to compositions comprising HSCs and Wharton's Jelly mesenchymal stem cells (WJSCs). The composition can further comprise a cell culture medium that has been conditioned with WJSCs.

Wharton's jelly mesenchymal stem cells and uses thereof

The present invention relates to methods for the identification and/or quantification of biomolecule(s). There is also provided a novel method of identifying and/or quantitating biomolecule(s) in a proliferative cell disorder by providing at least one cyst fluid sample and determining the expression of haptoglobin protein, derivative, mutant and/or fragment thereof.

Diagnostic biomolecule(s)

Growing community of inventors

Singapore, Singapore

Arijit Biswas