Cardiac Pacemakers, Inc.

Arienne P Simon

Andrew L De Kock

James Q Feng

Larry L Hum

Jeannette C Polkinghorne

Raymond Gessler

Joseph A Cihlar

Tolga Tas

Erin Kristen Webb

Joseph J Schachtner

Mitchell L Horn-Wyffels

Joseph J Nelsen

Erin K Webb

A solventless method for forming a coating on a medical electrical lead is described. The method includes combining particles of a therapeutic agent with a polymeric material in a flowable form in the absence of a solvent to form a uniform suspension. A predetermined amount of the suspension is dispensed onto a portion of the lead and is then cured to form the therapeutic agent eluting layer. Additional layers such as a primer layer, fluoro-opaque layer and/or a topcoat layer can be formed using the solventless method. Employing a solventless method may avoid contraction of the layer being formed due to solvent evaporation during the curing process, and may facilitate greater control over the thickness of the therapeutic agent eluting coating.

Solventless method for forming a coating on a medical electrical lead body

The various embodiments disclosed herein relate to medical electrical leads. More specifically, certain embodiments relate to leads having one or more drug-eluting components that are overmolded or otherwise positioned on the lead. Other embodiments relate to leads having one or more patterned surfaces, including some leads with one or more patterned surfaces over which one or more drug-eluting components are positioned. Further implementations relate to leads having one or more overmolded patterned surfaces, including some embodiments in which the overmolded surfaces contain at least one drug-eluting component.

Overmolded components for implantable medical leads and related methods

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Harrison City, PA, United States of America

Arienne P Simon