Kci Licensing, Inc.

Kimberly-clark Worldwide, Inc.

Archel A Ambrosio

Joanna Payne

Royce W Johnson

Dave Allen Soerens

Larry D Swain

Sohail Malik

Sharon Linda Greene

Cameron G Rouns

Rosann M Matthews Kaylor

Sharon L Greene

A fiber-microsphere composite scaffold including a first layer of material selected from one of a layer of bioresorbable microspheres and a layer of bioresorbable fibers; and a second layer of material selected from the other of the layer of bioresorbable microspheres and the layer of bioresorbable fibers. A fiber-microsphere composite scaffold reduced pressure tissue treatment apparatus is also included as well as methods for making fiber-microsphere composite scaffolds.

Fiber-microsphere bioresorbable composite scaffold for wound healing

Provided is a flowable bioresorbable tissue dressing comprising a gas-forming porogen and a gel or gel-forming solution. Also provided is kits for preparing the above-described tissue dressing. Further provided are methods of treating a tissue site of a mammal with the above dressing. Also provided is a reduced pressure delivery system for applying a reduced pressure tissue treatment to a tissue site.

Bioresorbable foaming tissue dressing

Methods, system and compositions for making and using a bioresorbable linked dressing made of bioresorbable microspheres in various configurations are provided for use in applying reduced pressure to a wound site. The methods include manufacture of a bioresorbable dressing comprising a casing and bioresorbable microspheres in the form of a rope shape. Further, the casing of the dressing comprises pores formed by a porogen system that may be activated by external to the wound or formed in situ within the wound site. The shape of the dressing allows the dressing to be placed into the wound site such that it fills the shape and size of the wound. Embodiments include formation of various rope dressing and their use in conjunction with reduced pressure therapy.

Porous bioresorbable rope shaped wound dressing comprising microparticles and reduced pressure source

A reduced pressure delivery system for applying a reduced pressure to a tissue site includes a manifold delivery tube having a passageway and a distal end, the distal end configured to be percutaneously inserted and placed adjacent the tissue site. A flowable material is provided and is percutaneously deliverable through the manifold delivery tube to the tissue site. The flowable material is capable of filling a void adjacent the tissue site to create a manifold having a plurality of flow channels in fluid communication with the tissue site. A reduced pressure delivery tube is provided that is capable of fluid communication with the flow channels of the manifold.

System and method for percutaneously administering reduced pressure treatment using a flowable manifold

Method of promoting new tissue growth and/or wound healing using bioresorbable dressing comprising microspheres or microparticles

Porous bioresorbable linked dressing comprising microspheres and methods of making same

A multi-layer reduced pressure delivery apparatus is provided for applying reduced pressure tissue treatment to a tissue site. The multi-layer apparatus includes a tissue contact layer, a release layer, and a manifold layer. The tissue contact layer includes a scaffold adapted to contact the tissue site, the release layer includes a water-soluble polymer and a plurality of flow channels, and the manifold layer includes a distribution manifold. The release layer is positioned between the tissue contact layer and the manifold layer to allow easy release of the manifold layer from the tissue contact layer following the administration of reduced pressure tissue treatment.

Biocompatible wound dressing

Methods of making porous bioresorbable dressing comprising casing comprising microspheres

A multi-layer reduced pressure delivery apparatus is provided for applying reduced pressure tissue treatment to a tissue site. The multi-layer apparatus includes a tissue contact layer, a release layer, and a manifold layer. The tissue contact layer includes a scaffold adapted to contact the tissue site, the release layer includes a hydrogel-forming material and a plurality of flow channels, and the manifold layer includes a distribution manifold. The release layer is positioned between the tissue contact layer and the manifold layer to allow easy release of the manifold layer from the tissue contact layer following the administration of reduced pressure tissue treatment.

A wound dressing includes a first layer located adjacent the wound and which comprises a material that is bioabsorbable, porous and adapted for serving as a scaffold for cell attachment and proliferation; and a second layer which is in contact with the first layer and which comprises an absorbent, gel forming material adapted for serving as a barrier to cell adhesion and penetration. A method of treating a wound with the dressing is also disclosed.

Bioabsorbable wound dressing

Coatings are formed by applying to article a copolymer of a water soluble base polymer having graft polymerized thereto an organic moiety that includes a group that reacts with water to form a silanol group, and then curing the copolymer to form a crosslinked hydrogel coating that is absorbent, lubricious and substantially non-water soluble. Coating compositions, coated articles the subject coatings are also described.

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San Diego, CA, United States of America

Archel A Ambrosio