Pacesetter, Inc.

Spinal Modulation, Inc.

St. Jude Medical Luxembourg Holdings Smi S.a.r.l.

April C Pixley

Cary W R Campbell

Steven T Brandon

Pajhand Iranitalab

Yongjian Wu

Timothy S Olson

Lynn H Elliott

Jeffrey M Alves

Michael O Williams

Anne M Shelchuk

Jeffery M Kramer

Jianchun Yi

Shohan T Hossain

Jeyakumar Subbaroyan

Curtis A Knight

Elisabeth M Clem

Christopher Pontiga

Youngjian Wu

Erica Lundmark

Chris Pontiga

Cary Wr Campbell

Specific embodiments of the present invention are for use by a base station (BS) that enables power efficient wireless radio frequency (RF) communication between the BS and a medical device (MD), which may or may not be an implantable medical device (IMD). In an embodiment, once a communication session is established between the BS and the MD, the BS selectively turns a drop link mode on and off. The drop link mode is a communication mode that while turned on (i.e., enabled) reduces and preferably minimizes the length of time that an RF link is maintained between the BS and the MD. In accordance with an embodiment, at any given time during a communication session the drop link mode is either turned on (i.e., enabled) or turned off (i.e., disabled).

Power efficient wireless RF communication between a base station and a medical device

Certain embodiments described herein enable a base station (BS) and a medical device (MD) to establish a radio frequency (RF) link using any one of a plurality of different RF channels. The MD sniffs the RF channels over which a BS may send a link request, and tunes to the RF channel identified, as a result of the sniffing, as the channel over which a BS may be transmitting a link request. The MD may also demodulate a signal received over the RF channel to which the MD is tuned, and determine, based on a portion of the demodulated signal including a channel identifier, a specific one of the RF channels over which a BS is actually transmitting. This enables the MD to change the channel to which it is tuned if it determines that it is not tuned to the RF channel over which a BS is actually transmitting.

Establishing an RF link between a base station and a medical device

Embodiments of the present invention concern the timing of sending one or more commands to control circuitry of a multi-electrode lead (MEL). In one embodiment, the one or more commands are sent to control circuitry within the MEL during a predetermined portion of a cardiac pacing cycle to avoid potential problems of prior systems that were not synchronized with the cardiac pacing cycle. In one embodiment, the one or more commands are sent when cardiac tissue is refractory from a cardiac pacing pulse, to prevent the command(s) from potentially undesirably stimulating cardiac tissue. The command sending can occur such that the one or more commands are sent between instances when sensing circuitry of the implantable cardiac stimulation device is being used to obtain one or more signals indicative of cardiac electrical activity, to prevent interference between the one or more commands with the signals indicative of cardiac electrical activity that are sensed.

Systems and methods to synchronize commands sent to a multi-electrode lead (MEL) with a portion of a cardiac pacing cycle

Methods and systems described herein can be used to automatically turn on and off stimulation of a target dorsal root ganglion (DRG) and/or adjust stimulation parameters. At least one of an input signal (indicative of an electrical field resulting from an electrical signal propagated by adjacent distal sensory nerve fibers toward the target DRG), an output signal (indicative of an electrical field resulting from an electrical signal propagated by adjacent proximal sensory nerve fibers away from the target DRG) or a DRG signal (indicative of an electrical field produced by cell bodies of primary sensory neurons within the target DRG and resulting from an electrical signal propagated by sensory nerve fibers within the target DRG) is/are obtained and analyzed. Delivery of electrical stimulation is turned on and off and/or at least one of pulse amplitude, pulse width and/or pulse repetition rate is/are adjusted based on results of the analysis.

Methods and systems for automatically turning on and off DRG stimulation and adjusting DRG stimulation parameters

Methods and systems are provided for configuring a Multi-Electrode Lead (MEL) that includes N groups of electrodes, with each of the N groups of electrodes including at least M electrodes, where N&#x2267;2 and M&#x2267;2. Sent via the MEL is a first communication sequence of bits that includes N groups of bits, with each of the N groups of bits corresponding to a different one of the N groups of electrodes and specifying which electrode(s), if any, within the group of electrodes is to be configured as an anode. Also sent via the MEL is a second communication sequence of bits that includes N further groups of bits, with each of the N further groups of bits corresponding to a different one of the N groups of electrodes and specifying which electrode(s), if any, within the group of electrodes is to be configured as a cathode.

Systems and methods to configure a multi-electrode lead

An implantable cardiac stimulation device is equipped with a hardware elastic buffer. In an exemplary device, the hardware elastic buffer comprises SRAM and a SRAM controller. The device optionally includes averaging, concatenating, filling and/or other features.

Implantable stimulation device equipped with a hardware elastic buffer

A ventricular tachycardia (VT) complex is distinguished from a sinus tachycardia or a supraventricular tachycardia. A template based on morphology of a normal sinus rhythm is collected. A test signal is compared against the template to determine how closely the test and template signals correspond based on morphology. The comparison is done based on peak information in the template and the test signal. A score is generated to indicate the degree of similarity between the template and the test signal. The peak information is extracted as follows. First, a group of three consecutive peaks having a largest cumulative peak amplitude is located in the template and in the test signal. The polarity, position and area of each peak within the group is then determined. The area of each peak is normalized. The polarities, positions and normalized areas represent the peak information that is used for comparison.

System and method for waveform morphology comparison

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Los Altos, CA, United States of America

April C Pixley