Lallemand Hungary Liquidity Management LLC

Teknologian Tutkimuskeskus Vtt Oy

Stellenbosch University

Anu Koivula

Merja Elisa Penttila

Vineet Rajgarhia

John E McBride

Liisa Viikari

Allan C Froehlich

Elena E Brevnova

Matti Siika-Aho

Mark Mellon

Marja Ilmen

Emily Stonehouse

Riaan Den Haan

Haowen Xu

Kristen M Deleault

Alan Benjamin Gilbert

John S Bardsley

Pia Qvintus-Leino

Kirsi Immonen

Sanni Voutilainen

Deidre Willes

Tiina Pakula

Harry Boer

Maria Smolander

Jaana Uusitalo

Nina Aro

Kaisa Marjamaa

Matti Valkiainen

The present invention discloses a polypeptide having beta-glucosidase activity. The activity is retained also in high glucose concentration. The invention also discloses an isolated polynucleotide, a nucleic acid construct and a recombinant host usable in production of said polypeptide, and a method for producing the polypeptide. Further the invention discloses compositions including the polypeptide and method of using the polypeptide in hydrolysis or synthesis.

Beta glucosidase with high glucose tolerance, high thermal stability and broad PH activity spectrum

The present invention is directed to cellulytic host cells. The host cells of the invention expressing heterologous cellulases and are able to produce ethanol from cellulose. According to the invention, host cells expressing a combination of heterologous cellulases can be used to produce ethanol from cellulose. In addition, multiple host cells expressing different heterologous cellulases can be co-cultured together and used to produce ethanol from cellulose. Furthermore, the invention demonstrates for the first time the ability ofto produce ethanol from cellulose. The yeast strains and co-cultures of yeast strains of the invention can be used to produce ethanol on their own, or can also be used in combination with externally added cellulases to increase the efficiency of saccharification and fermentation processes.

Yeast expressing cellulases for simultaneous saccharification and fermentation using cellulose

Host cells, comprisingexpressing heterologous cellulases produce ethanol from cellulose In addition, multiple host cells expressing different heterlogous cellulases can be co-cultured together and used to produce ethanol from cellulose The recombinant yeast strains and co-cultures of the yeast strains can be used to produce ethanol on their own, or can also be used in combination with externally added cellulases to increase the efficiency of sacchanfication and fermentation processes.

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Helsinki, Finland

Anu Koivula