Koninklijke Philips Corporation N.V.

National Institutes of Health

Profound Medical Inc.

Antti Johannes Viitala

Max Oskar Köhler

Matthew R Dreher

Mika Petri Ylihautala

Pavel Sergeyevich Yarmolenko

Ari Ilkka Mikael Partanen

Julia Kristina Enholm

A therapeutic apparatus () comprising a high intensity focused ultrasound system () for heating a target zone (). The therapeutic apparatus further comprises a magnetic resonance imaging system (). The therapeutic apparatus further comprises a memory () containing machine executable instructions () for execution by a processor (). Execution of the instructions cause the processor to: generate () heating commands () which cause the high intensity focused ultrasound system to sonicate the subject; repeatedly acquire () magnetic resonance data () during execution of the heating commands; repeatedly calculate () a spatially dependent parameter (); and repeatedly modify () the heating commands in accordance with the spatially dependent parameter such that within the target zone the spatially dependent parameter remains below a first predetermined threshold and above a second predetermined threshold.

Therapeutic apparatus and method for heating a subject

The invention provides for a medical apparatus () comprising a high intensity focused ultrasound system (), a memory containing instructions, and a processor. Execution of the instructions causes the processor to receive () surface data () descriptive of the location of a surface (). The surface data defines the location of the heating volume. Execution of the instructions further cause the processor to determine () a set of transducer switching commands () using the heating location data and an ultrasound transducer element model () and control () the high intensity focused ultrasound system with the set of transducer switching commands to heat the heating volume. The set of transducer switching commands comprises an intensity level for the multiple ultrasound transducer elements either above or below a predetermined intensity for controlling a cross sectional shape of the heating volume to encompass the surface.

Medical apparatus for heating a heating volume defined by a surface

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Espoo, Finland

Antti Johannes Viitala