Bayer Aktiengesellschaft

Bayer Akteingesellschaft

Antonius Lobberding

Wolfgang Springer

Axel Kretschmer

Burkhard Mielke

Udo Stropp

Eberhard Kuckert

Manfred Plempel

Gunther Beck

Herbert Hugl

Bruno Bomer

Florin Seng

Ludger Heiliger

Eckhard Schwenner

Jorg Baumgarten

Helga Rubsamen-Waigmann

Hans-Ulrich Siegmund

Christoph Schwemler

Walter Strube

Heinz Kolbl

Gamal K Mikhail

Peter Thein

Lothar Biesert

Thorsten Potter

Haryadi Suhartono

Gunther Franke

Hans G Rast

Reinhard Kanne

Axel C Heitmann

The present invention concerns photochemical labelling reagents comprising a digoxigenin derivative and a furocoumarin derivative bound via a spacer. The labelling reagent can be used in gene diagnostic.

Photochemical labelling of nucleic acids with digoxigenin reagents and

The invention relates to nucleic acid-binding oligomers possessing C-branching of the general formula (I) ##STR1## and to the corresponding monomers, whose radicals have the meaning given in the description, and to their use as medicaments or diagnostic aids.

Nucleic acid-binding oligomers possessing C-branching for therapy and

The invention relates to polynucleotides which contain pseudorabies virus sequences, in particular sequences from the gII region of PRV, in the antisense orientation, their preparation and their use.

Pseudorabies virus (PRV) polynucleotides and their use for preparing

Polynucleotide and oligonucleotide probes are described for the diagnostic investigation of mycoses which are caused by Candida albicans. These gene probes are complementary to parts of the genome of C. albicans and are suitable for identifying C. albicans nucleic acids in any sample material, even that which has been amplified. They do not hybridise with nucleic acids from other fungi, bacteria, animals or plants. Processes are described for the diagnosis of C. albicans in clinical samples as well.

Specific gene probes and processes for the diagnostic investigation of

For the detection and quantitative determination of nitrosomonas strains in wastewaters and soils, a gene probe is used which, by virtue of its complementary sequences, only hybridizes with parts of the genome of nitrosomonas strains from wastewater or soil samples and does not produce a positive hybridization signal with parts of the genome of other bacteria and the hybridized nucleic acid is quantitatively determined by means of a known label of the gene probe and thus provides a direct measure of the content of nitrosomonas strains in the wastewater or soil sample.

Method for the detection and quantitative determination of nitrosomonas

Coumarin deviatives of the formula ##STR1## in which R.sup.1 denotes cyano,

Coumarin derivatives, process for their preparation, their use and

The present invention relates to polymer dyestuffs, i.e. polymer-bound dyestuffs, to a process for their preparation and to their use, for example as markers in analytical procedures. Polymer dyestuffs contain linkable functional groups and are water-soluble under customary conditions of analysis. The polymer portion is usually responsible for this water solubility. The dyestuffs per se are often water-insoluble.

Polymer dyestuffs and preparation and use thereof

Novel oligophosphates with an antiviral action of the formula ##STR1## in which n is 3-50,

Oligophosphates with an antiviral action

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Wuppertal, Germany

Antonius Lobberding