Safetraces, Inc.

Lawrence Livermore National Security, LLC

Compact Particle Acceleration Corporation

Other

Antonios Zografos

Laurie M Clotilde

George Roy Farquar

Peter Mattei

John Mark Carter

Vladimir Andreevich Joshkin

Dave Pearson

A pathogen surrogate, formed by a DNA tag or bar code and a carrier, is described for use in the validation and verification of sanitation, such as in food processing operations and for wash water systems for fresh produce. The carrier material is selected so that the pathogen surrogate mimics the behavior of a pathogen when subjected to a sanitation operation. One or more surrogates can be introduced in to an environment, which is then subjected to sanitation process, followed by a detection process using the DNA tag of the surrogate.

Pathogen surrogates based on encapsulated tagged DNA for verification of sanitation and wash water systems for fresh produce

A sanitation management system maintains records of exemplary locations on an item to be sanitized and indicates those locations to a person or system charged with applying a pathogen surrogate prior to a sanitation process. The sanitation management system maintains records of where the pathogen surrogate was applied prior to the sanitation process. Following the sanitation process, the sanitation management system indicates to an inspector, or an inspection system, locations of where the pathogen surrogate was applied for the purpose of facilitating testing of the sanitation process by checking for the presence of the pathogen surrogate at some or all of those locations. This can ensure that the inspection process is relevant to the sanitation process and less likely to generate false negatives where the inspection finds a lack of the pathogen surrogate not due to cleaning, but due to lack of application of the pathogen surrogate.

Sanitation monitoring system using pathogen surrogates and surrogate tracking

Material in a supply chain is tracked by a method of applying a DNA taggant set to a first batch of the material produced by a first supplier of the material. The DNA taggant set corresponds to a tag string corresponding to the first supplier. The first batch is aggregated with a second batch to create an aggregated lot. A sample is selected from the aggregated lot and tested to determine a DNA taggant set of the sample. After selecting a sample from the aggregated lot, the sample may be labeled with a grade and then placed in a receptacle corresponding to the grade.

Product tracking and rating system using DNA tags

A dispersant system comprises a plurality of taggant vessels, each having a taggant that corresponds to a position in a tag string and a computer controller convert the tag string into a selection of a taggant set while computer-controlled valves allow or block a flow of taggants to a manifold output tube. From the output tube, a mix of the taggants flow to form a dispersant formed according to the tag string. A nozzle disperses the dispersant onto an object to be tagged, possibly atomized with air. The taggant can comprise a DNA taggant comprising a static portion and a dynamic portion that is unique to each tag string position. Tag strings for adjacent lots might have a low Hamming distances to reduce cross-contamination and/or have redundancy for error detection and correction and selected so that consumption of taggants evens out over the plurality of taggant vessels.

Dispensing system for applying DNA taggants used in combinations to tag articles

Food distributed to consumers through a distribution chain may be traced by tagging the food with DNA tags that identify the origin of the food, such as the grower, packer and other points of distribution, and their attributes. This makes it much quicker and easier to trace the food in case of food contamination or adulteration. Preferably these attributes indicate the field, location, crew and machine used to grow and process the food, and the dates of the various steps of food harvesting, processing and distribution. Natural or synthetic DNA pieces may be used to tag items, including food items. Multidigit binary or other types of bar codes may be represented by multiple types of DNA. Each digit of the bar code may be represented by one, two or more unique DNA pieces.

DNA based bar code for improved food traceability

A blumlein assembly incorporating a solid-state switch is presented. In the exemplary embodiment, a semiconductor switch is placed between first and second conducting strips, with dielectric material filling in the space between the strips on either side of the switch. A third conductive strip, parallel to the other two strips, is separated from the middle one of the strips by another dielectric layer. Rather than having the switch attach directly to the dielectric material on either side, a holder or carrier structure is used, which may be formed of several pieces or of a monolithic structure. The holder is formed of a material whose dielectric constant is closer to that of the switch than the dielectric material on either side, but whose boundary with the dielectric on either side has at least a portion that extends in a non-orthogonal direction with respect to the conducting strips. The arrangement allows the structure to withstand higher electric field levels without breakdown. The exemplary switch is light activated and the holder structure also includes ferrules on either side of the holder, by which optic fibers can be optically coupled with the switch. The switch extends to either side beyond the conductive strips, so that the ferrules are not placed between these strips to again allow for the use of higher field values.

Blumlein assembly with solid state switch

Circuitry is presented for use in the pulse-forming lines of compact linear accelerators of charged particles. This presents devices that can provide high-voltage radio-frequency pulses in the range of from a few volts to megavolts for charged particle accelerators. The devices can use as input an external charge voltage and an optical pulse to create output RF pulses with a peak voltage that is increased over the input voltage. The exemplary embodiment presents a circuit of pulse forming lines for compact linear accelerator that includes an opto-switch and RF transmission lines that form a pulse shaper and a ladder-like pulse multiplier unit, with or without an output shaper.

Growing community of inventors

Oakland, CA, United States of America

Antonios Zografos