Isp Investments Inc.

Scimed Life Systems, Inc.

Lubrizol Advanced Materials, Inc.

Meadox Medicals, Inc.

Antonio Moroni

William Drefko

Nadhamuni G Nerella

David J Lentz

Gary L Loomis

Gregory Du Browny

Jennifer DePreker

Elena S Draganoiu

The disclosed technology provides improved adhesive composition of use with dentures. These improved compositions include (a) a cross linked poly(acrylic) acid polymer, in combination with (b) a carbomethylcellulose (CMC) component and/or (c) an adherence promoting component. The compositions balance the many competing goals for effective denture adhesives, including adhesive strength and dispensing viscosity, without the need for zinc.

Denture adhesives

Prostheses with improved chemical and mechanical properties manufactured that includes a radiation resistant and hydrolytically stable biocompatible fabric having outer and first and second ends with a textile fabric that includes a naphthalene dicarboxylate derivative polymer having the general formula: wherein Rand Rare the same or different groups and are independently selected from the naphthalene dicarboxylate derivative repeating unit (I), a hydrogen radical and a methyl radical. Ris an alkylene radical having 1 to 6 carbon atoms; n is from 10 to 200. Also contemplated are implantable prostheses that are flat constructions useful as patches and filters or tubular constructions useful as vascular grafts. A further aspect of this invention provides a method for making a radiation and thermal resistant and hydrolytically stable, steam sterilizable biocompatible prosthesis.

Implantable prostheses with improved mechanical and chemical properties

A tablet coating composition including a mixture of (a) sodium alginate and (b) a polyvinylpyrrolidone-vinyl acetate copolymer, and, optionally, (c) hydroxypropylmethyl cellulose, and/or hydroxypropyl cellulose.

Tablet coating composition

A synergistic filler composition for making pharmaceutical tablets of sufficient tablet hardness at low compression force, and low friability, to preclude damage to the tablet upon further processing, and without requiring a substantial increase in the size of the tablet, comprising (a) a PVP-VA copolymer and (b) a microcrystalline cellulose.

Synergistic filler composition

A pH-dependent sustained release, drug delivery composition capable of being formed into tablets or pellets, wherein the release is controlled by a diffusion barrier formed by the interaction of a pH-dependent gelling material and a pH-independent non-gelling material, comprising a polymer matrix comprising, by weight, (a) 10 to 50% sodium alginate, (b) 2 to 15% propylene glycol alginate and (c) 40 to 80% of a pharmaceutical medicament.

pH-dependent sustained release, drug-delivery composition

A radiopaque polymeric composition useful as a polymer coating on a substrate. The compositions are designed to be bioabsorbable and are particularly useful on implantable medical devices, such as vascular prostheses and the like.

Radiopaque compositions for visualization of medical devices

A bioresorbable sealant composition useful for impregnating implantable soft-tissue prostheses includes at least two polysaccharides in combination to form a hydrogel or sol-gel. The sealant compositions may optionally include a bioactive agent and/or be cross-linked subsequent to application of these compositions to the substrate surface.

Growing community of inventors

Morris Plains, NJ, United States of America

Antonio Moroni