Other

Antonina I Polezhaeva

Mikhail D Mashkovsky

Robert G Glushkov

Irina A Ivanova

Vladimir G Granik

Jury G Bobkov

Roza B Parimbetova

Alexandr S Losev

Lidia F Roschina

Tatyana V Stezhko

Maria Nikolaevna Preobrazhenskaya, Administrator

Galina Nikolaevna Litova

Valentina Georgievna Nyrkova

Tatyana Vladimirovna Gortinskaya

Maria Nikolaevna Schukina, Deceased

Larisa Nikolaevna Bondar

A novel compound, namely, 1-thiocarbamylmethylpyrrolidine-2-thione has the following formula: ##STR1## A process for preparing said compound comprises reacting a derivative of pyrrolidone-2 of the general formula: ##STR2## wherein R is nitrile or carbamoyl, with phosphorus pentasulphide in an inert non-polar solvent at a temperature above room temperature, followed by treatment of the resulting precipitate with water upon boiling and isolation of the desired product. The compound according to the present invention exhibits antihypoxic and nootropic activity.

1-thiocarbamylmethylpyrrolidine-2-thione, process for preparing

1-Thiocarbamoylmethylpyrrolidine-2-thione, medical compositions of, and

An antidepressant medicinal preparation comprises as an active principle, dihydrochloride-2-(2'-diethylaminoethoxy)-10-methyl-3,4-diazaphenoxiazine having the following formula: ##EQU1## AND WHICH IS COMBINED WITH A PHARMACEUTICAL CARRIER.

Antidepressant medicinal preparation

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Moscow, Russia

Antonina I Polezhaeva