University of Miami

Nogra Pharma Limited

Converge Biotech Inc.

Antonello Pileggi

Camillo D Ricordi

Luca Inverardi

Christopher A Fraker

Peter Buchwald

Giovanni Monteleone

Alice Tomei

Ernesto A Pretto, Jr

Kyota Fukazawa

Jeffrey Alan Hubbell

Nicholas S Bodor

Norma Sue Kenyon

Fabio Grassi

Paul Latta

Cheryl Stabler Anderson

Disclosed herein are methods for treating/and or preventing diabetes using a specific inhibitor of SMAD7 expression or function. Also disclosed are methods of promoting organ and/or cell, e.g., pancreatic islet cell, survival after transplantation using a specific inhibitor of SMAD7 expression or function.

Methods of treating diabetes and/or promoting survival of pancreatic islets after transplantation

A stable liquid nanoemulsion of a volatile gas anesthetic, such as, isoflurane or sevoflurane, is disclosed which is effective in inducing and maintaining a state of anesthesia and/or general anesthesia in a patent. A method of preparation of stable liquid formulations of volatile gas anesthetics is presented, as well as a method for directly testing the concentration of a volatile gas anesthetic in a stable liquid formulation. A kit comprising an amount of a stable liquid formulation of a volatile gas anesthetic, and the non-specialized equipment for administration of the same to a patient, either in an operating room environment or in the field, is also described herein.

Stable liquid formulations of volatile gas anesthetics

A device () for receiving implanted biological material includes a mechanoprotective surface () defining an adjacent space, an assembly () for locally delivering media to said space, and a pump or slow/sustained release reservoir structure () operatively coupled to the assembly. The device may comprise an additional plunger body for being disposed in said space. The implanted biological material may be encapsulated or non-encapsulated.

Therapeutic hybrid implantable devices

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Aventura, FL, United States of America

Antonello Pileggi