Novartis Vaccines & Diagnostics, Gmbh

Other

Torosantucci, Antonella

Cassone, Antonio

Antonella Torosantucci

Antonio Cassone

Anti-&#x3b2;-1,3-glucan antibodies have been found to be protective against systemic fungal infection with. The present invention provides monoclonal antibodies that bind to &#x3b2;-1,3-glucan, hybridoma cell lines producing the antibodies, compositions comprising the antibodies and methods of using such antibodies for treatment of microbial infections, particularly againstandinfections. The antibodies of the present invention are not specific for &#x3b2;-1,6-glucan.

Protective anti-glucan antibodies with preference for &#x3b2;-1,3-glucans

Anti-&#x3b2;-1,3-glucan antibodies have been found to be protective against systemic fungal infection with. The present invention provides monoclonal antibodies that bind to &#x3b2;-1,3-glucan, hybridoma cell lines producing the antibodies, compositions comprising the antibodies and methods of using such antibodies for treatment of microbial infections, particularly againstandinfections. The antibodies of the present invention are not specific for (&#x3b2;-1,6-glucan.

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Rome, Italy

Antonella Torosantucci