Sandoz Gmbh

Anthony Williams, Inc.

Dieter Becker

Rainer Alles

Friedrich Karl Mayer

Stefan Hirsch

Oskar Kalb

Ernst Ulrich Kolle

Jean-Daniel Bonny

Anton Stutz

Peter Stutz

Peter Nussbaumer

Josef Gottfried Meingassner

Maximilian Grassberger

Helmut Hamberger

Adrian Stephen

Anthony Williams

The compounds of formula I, ##STR1## have been found to have excellent topical activity. They are thus indicated for use in the topical treatment of inflammatory and hyperpoliferative skin diseases and of cutaneous manifestations of immunologically-induced illnesses, such as psoriasis.

Use of 11,28-dioxa-4-azatricyclo[22.3.1.0.sup.4,9 ]octacos-18-ene

The invention concerns the compounds of formula I ##STR1## wherein the substituents have various significances, in free form and, where such forms exist, in salt form. The compounds have potent antihyperproliferative/antiinflammatory and anticancer activity.

Bis(phenyl)ethane derivatives

New use of 11,28-dioxa-4-azatricyclo[22.3.1.0.sup.4,9 ]octacos-18-ene derivatives and pharmaceutical compositions containing them The compounds of formula I, ##STR1## have been found to have excellent topical activity. They are thus indicated for use in the topical treatment of inflammatory and hyperpoliferative skin diseases and of cutaneous manifestations of immunologically-induced illnesses, such as psoriasis.

Compounds of formula I ##STR1## wherein R.sub.1 represents a group of formula ##STR2## and R.sub.2 represents hydrogen or lower alkyl, or

Amine derivatives, processes for their production and their use

Compounds of formula I ##STR1## wherein R.sub.1 represents a group of formula ##STR2## whereby R.sub.4 and R.sub.5 are the same or different and represent hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl and X represents oxygen, sulfur, imino, lower alkylimino, --(CH.sub.2)--, --(S.CH.sub.2)-- or --(O.CH.sub.2)--,

Bicyclic allylether derivatives, processes for their production and

Benzothienyldialkylallylamines wherein the amine side chain is attached to the ring via an alkyl radical and is either in 4-, 5-, 6- or 7-position or if not bears tertiary alkylethynyl or alkenylethynyl as its terminal group, which are useful, in particular, as anti-mycotic agents.

Benzothienylallylamines processes for their production and their use as

The present invention provides propenylamines useful as anti-mycotic agents.

Propenylamines, processes for their production and pharmaceutical

Silyl-alkyn-en-ylamine derivatives which possess pharmaceutical in particular anti-mycotic activity.

Growing community of inventors

Vienna, Austria

Anton Stutz