Applied Nanosystems B.v.

Anton Steen

Cornelis Johannes Leenhouts

Jan Kok

Girbe Buist

Oscar Paul Kuipers

Ranjan Ramasamy

Methods for improving binding of a proteinaceous substance to cell-wall material of a Gram-positive bacterium are disclosed. The proteinaceous substance includes an AcmA cell-wall binding domain, homolog or functional derivative thereof. The method includes treating the cell-wall material with a solution capable of removing a cell-wall component such as a protein, lipoteichoic acid or carbohydrate from the cell-wall material and contacting the proteinaceous substance with the cell-wall material.

Immunization with bacterial ghost-based vaccines

Method to provide bacterial ghosts provided with antigens

Bacterial ghosts provided with antigens

Growing community of inventors

Groningen, Netherlands

Anton Steen