Boehringer Ingelheim International Gmbh

Anton Pekcec

Doris Riether

Niklas Heine

Marco Ferrara

Janet Rachel Nicholson

Uta Friederike Lessel

Stefan Scheuerer

Georg Dahmann

Stefan Peters

Kai Gerlach

Roland Pfau

Dieter Wiedenmayer

Stefan Just

Heiko Sommer

Riccardo Giovaninni

Julia Schlichtiger

Thorsten Lehmann

Johann Faustus Du Hoffmann

Christoph Hohn

Christian Specker

Uta Lessel

The present invention relates to compounds of formula I a process for their manufacture, pharmaceutical compositions containing them and their use in therapy, particularly in the treatment and/or prevention of conditions having an association with the function of metabotropic glutamate receptor subtype 4 (mGluR4). A, R, R, R, R, Rand Rhave meanings given in the description.

Substituted pyrazine-carboxamide derivatives

This invention relates to compounds of formula (I), a process for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions having an association with the orexin sub-type 1 receptor. Ar, R, R, R, R, R, Rand Rhave meanings given in the description. 

N-[(pyridyloxy)propanyl]benzamides

This invention relates to compounds of formula (I), a process for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions having an association with the orexin sub-type 1 receptor. Arand Arhave meanings given in the description. 

N-[(heteroaryloxy)propanyl]heteroaryl carboxamides as antagonists of orexin subtype 1 receptor activity

The present invention relates to novel N-[(Pyrimidinylamino)propanyl]- and N-[(Pyridinylamino)propanyl]arylcarboxamide derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, particularly in the treatment or prevention of conditions having an association with the orexin sub-type 1 receptor.

N-[(Pyrimidinylamino)propanyl]-and N-[(Pyridinylamino)-propanyl]arylcarboxamides

This invention relates to compounds of formula I a process for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions having an association with the orexin sub-type 1 receptor. Ar, R, Rand Rhave meanings given in the description.

N-[(pyrazinyloxy)propanyl]benzamides as antagonists of orexin subtype 1 receptor activity

This invention relates to compounds of formula (I), a process for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions having an association with the orexin sub-type 1 receptor. Ar, R, R, R, R, Rhave meanings given in the description. 

N-[(pyrimidinyloxy)propanyl]benzamides

The present invention relates to novel N-[(Pyrimidinylamino)propanyl]- and N-[(Pyrazinylamino)-propanyl]arylcarboxamide derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, particularly in the treatment or prevention of conditions having an association with the orexin sub-type 1 receptor.

N-[(pyrimidinylamino)propanyl]-and N[(pyrazinylamino)proppanyl]arylcarboxamides

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Munich, Germany

Anton Pekcec