Boehringer Ingelheim Gmbh

Boehringer Ingelheim Kg

Boehringer Ingelheim International Gmbh

Boehringer Ingelheim (canada) Ltd.

C. H. Boehringer Sohn

Anton Mentrup

Kurt Schromm

Ernst-Otto Renth

Wolfgang Hoefke

Werner Traunecker

Armin Fugner

Herbert Koppe

Richard Reichl

Peter Danneberg

Gojko Muacevic

Ilse Streller

Ludwig Pichler

Wolfram Gaida

Karl Zeile

Otto Thoma

Bruno Simoneau

Alexander Walland

Ernst Otto Renth

Wilhelm Frolke

Volker Jacobi

Gojko Mualcevic

Gojko Muaceic

Michele Liuzzi

The invention provides compounds of the formula 1 that are active against the HSV primase enzyme:

HSV primase inhibitors

Compounds of formula ##STR1## wherein the substituents are defined hereinbelow, useful in the treatment of bronchospasm are described.

New quaternary ammonium compounds, their preparation and use

Compounds of the formula ##STR1## wherein (a)

Pyridotriazoloquinazolines and triazolopyridoquinazolines useful as

Compounds of the formula ##STR1## wherein Het is ##STR2## n is an integer from 1 to 4, inclusive, preferably 2 or 3, R.sub.1 is H or acyl,

Heterocyclic compounds

Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are hydrogen or substituents of various types;

Intermediate 1-alkylenyl-1H-benzimidazol-2-one derivatives

1-phenyl-2-(heterocyclyl-alkyl-amino)-ethanols

Compounds of the formula ##STR1## wherein n is 1 or 2, R.sub.1 is hydrogen, --CO--R.sub.2 or --SO.sub.2 R.sub.3,

Bronchospasmolytic

Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, alkyl of 1 to 4 carbon atoms or trifluoromethyl;

1-(6,7-Dimethoxyquinazol-4-yl)semicarbazides

Compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2, which may be identical to or different from each other, are each independently hydrogen, straight or branched alkyl of 1 to 8 carbon atoms or arylmethyl; or

N-[1-(4-Amino-6,7-dialkoxy-2-quinazolinyl)-4-piperidy

Compounds of the formula ##STR1## wherein A is a single bond, ##STR2## R.sub.1 is --OH, --0--acyl, chlorine or hydrogen; R.sub.2 is hydrogen, methyl or ethyl;

(1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones

1-Aryloxy-2-hydroxy-3-((heterocyclic-substituted alkyl)-amino)-propanes

Racemic or optically active compounds of the formula

Aminoalkyl-substituted heterocycles

1-Aryloxy-2-hydroxy-3[(heterocyclic-substituted alkyl)-amino]propanes

The invention relates to compounds of general formula I ##STR1## (wherein R.sub.1 and R.sub.2, which may be the same or different, each represents a hydrogen atom or a (C.sub.1 -C.sub.4) alkyl group;

Growing community of inventors

Mainz-Kastel, Germany

Anton Mentrup