Tecan Trading Ag

Bsh Hausgerate Gmbh

Bsh Bosch Und Siemens Hausgerate Gmbh

Anton Mathes

Philipp Kleinlein

Michael Steffl

Gyoergy Wenczel

Olaf Ohlhafer

Wolfgang Streit

Siegmund Kramer

Waltraud Lamprecht

Stefan Hassfurter

Rudolf Beck

Albert Ostermaier

Josef Daburger

Hans-Arndt Freudigmann

Maximilian Fremerey

Josef Gius

Stefan Wrehde

Andreas Aigner

Markus Helminger

Robert Jaskolka

Ralf Fuchs

Andreas Hauser

Wolfgang Mayr

Timothy Mark Tracy

Florian Hoeck

Ali Utku Gökce

Mahir Erdem Deger

Michael Huber

Jürgen Fritz

Benedikt Steininger

Georg Stadler

Gottfried Schneiderbauer

Nina Rieperdinger

Muharrem ÜMit Caglin

Maximilian Mies

Robert Strobl

Andreas Brunner

Markus Kühnel

A device provides a hybridization chamber for hybridizing nucleic acid samples, proteins or tissue sections on a slide, and is an essentially rectangular body movable opposite the slide. The device includes a surface, lines for supplying and/or removing media, a specimen supply line and an agitating device. The agitation device includes at least one membrane which separates a pressure chamer to be fillable with a pressure fluid via one of the lines, from at least one agitation chamber connected via an agitation line to the hybridization chamber. The lines are continuously open so the media therein can permanently flow unhindered. Four such devices can be combined into a process unit for providing a hybridization chamber. Such unit is pivotable around an axis and has a holder with four seats, which is lockable in relation to a baseplate, one device being insertable into each one of the seats.

Device and process unit for providing a hybridization chamber

A device () is disclosed for providing a hybridization chamber (), for hybridizing nucleic acid samples, proteins, or tissue sections on a slide (), which is implemented so that it is movable in relation to this slide () and includes an annular sealing surface () for sealing the hybridization chamber () by being applied to a surface () of this slide (), lines () for supplying and/or removing media to and/or from the hybridization chamber (), and a specimen supply line (). The devices according to the invention include a media-separating agitation device () for moving liquids in relation to samples immobilized on the surface () of the slide (). Furthermore, process units () for hybridizing nucleic acid samples, proteins, or tissue sections and corresponding automatable systems including such process units () are disclosed.

Device for providing a hybridization chamber, and process unit and system for hybridizing nucleic acid samples, proteins, and tissue sections

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Neukirchen, Germany

Anton Mathes