Consortium Fur Elektrochemische Industrie Gmbh

Wacker Chemie Ag

Consortium F{umlaut Over (u)}r Elektrochemische Industrie Gmbh

Anton Candussio

Gerhard Schmid

August Bock

Elke Fritz-Langhals

Norbert Hampp

Johannes Freudenreich

Susanne Leonhartsberger

Georg E Schulz

Verena Schlensog

Dagmar Mayer

The present invention comprises a signal peptide with a cleavage site to a recombinant protein, wherein the last three amino acids before the cleavage site are alanine-phenylalanine-alanine (AFA).

Signal peptide for the production of recombinant proteins

Process for the preparation of heteroaryl aldehydes or heteroaryl ketones by reaction with heteroarylmethanols with the aid of a mediator and an oxidant, wherein the mediator is selected from the group of the aliphatic, cycloaliphatic, heterocyclic or aromatic NO, and NOH containing compounds.

Process for the preparation of heteroaryl aldehydes and heteroaryl ketones

A process for the preparation of vinyl, alkynyl or aryl aldehydes or vinyl, alkynyl or aryl ketones by reaction of vinyl-, alkynyl- or aryl- methanols with the aid of a mediator and an oxidant, wherein the mediator is selected from the group of the aliphatic, cycloaliphatic, heterocyclic or aromatic NO or NOH containing compounds.

Process for the preparation of aldehydes and ketones

An expression system can be regulated by acetate, pH and oxygen, which expression system includes a trans-acting regulator protein and a promoter which can be activated by this protein. Any desired structural genes are maximally expressed under the control of the expression system at an oxygen partial pressure, pO.sub.2, of 0-5% and a pH of 6.0-6.5, and in the presence of acetate at a concentration of 40-60 mM. There is also a process for preparing this expression system, and a process for using this expression system.

Expression system which can be regulated

A cyclodextrin glycosyltransferase (CGTase) which, in the conversion of starch or starch-like substrates to CD, produces .gamma.-CD in an increased amount, and whose protein sequence, in the region between amino acid position 180 and amino acid position 240, contains the amino acid sequence (SEQ ID NO: 1), where position 1 of the protein sequence is the beginning of the signal peptide of the CGTase and Xxx denotes a natural amino acid.

Modified cyclodextrin glycosyltransferases for producing

The alkalophilic bacteria (DSM 5853) possesses a maltopentaose producing amylase. The maltopentaose producing amylase, and its derivatives modified by gene manipulation, can be expressed in E. coli. These amylases facilitate the production of maltopentaose.

Biologically pure culture of maltopentaose forming amylase producing

A maltopentaose producing amylase, and its derivatives modified by gene manipulation, can be expressed in E. col. These amylases facilitate the production of maltopentaose.

Growing community of inventors

Munich, Germany

Anton Candussio