Pierre Fabre S.a.

Pierre Fabre Medicament

P. F. Medicament

Antoine Stenger

Henri Cousse

Gilbert Mouzin

Guy Pitet

Jean-Pierre Rieu

Bernard Bonnaud

Michel Morre

Mike Briley

Michel Briley

Philippe Chopin

Sylvano Casadio

The present invention concerns new 5-monoaryl as.-triazin-3-ones substituted in 2-position, a method of preparing them, and their use as medicaments. The compounds according to the present invention have general formula (I) ##STR1## in which: the bond represented by a dashed line indicates the presence of an optional double bond;

5-monoaryl as.-triazin-3-ones substituted in 2-position, and their use

The present invention relates to new 2-(arylalkyloxymethyl)morpholine derivatives, the preparation thereof and their application as drugs which are useful in the treatment of disorders of the central nervous system. The 2-(arylalkyloxymethyl)morpholine derivatives according to the invention correspond to the general formula (I): ##STR1## in which: Ar denotes an aromatic group and more especially the following radicals: ##STR2## in the case where Ar denotes a phenyl radical and R denotes a hydrogen atom, an alkyl, alkoxy or halogen group, a trifluoromethyl radical, a nitro or amino group, a hydroxy group or an arylalkyloxy group.

2-(arylalkyloxymethyl)morpholines and the central nervous system

The present invention concerns new derivatives of 1-aryl 2-aminomethyl cyclopropane carboxamides (Z) of general formula I: ##STR1## in which: R represents a hydrogen or halogen atom, a lower alkyl group, a lower alkoxy group, or a hydroxy. nitro or amino group;

1-Aryl 2-aminomethyl cyclopropane carboxyamide (Z) derivatives and their

The present invention relates to 2'-(ortho-chlorobenzoyl)-4'-chloroglycylanilides, compositions thereof, and their use as medicaments, e.g., as anxiolytic agents. The compounds of the invention have the general formula I ##STR1## in which R represents hydrogen or alkyl,

2'-(Orthochlorobenzoyl)-4'-chloroglycylanilides

Method of treating anxiety with

2'-(Orthochlorobenzoyl)-4'-chloroglycylanilides, compositions thereof,

The invention relates to new substituted 2-benzoyl-4-chloroglycinanilide derivatives, to a process for their production and to their use as medicaments. The new derivatives according to the invention correspond to the general formula ##STR1## in which: R may be a linear or branched alkyl group, preferably a lower alkyl group;

Substituted 2-benzoyl-4-chloroglycinanilide derivatives, a process for

The invention relates to new chemical compounds which can be used as analgesic drugs and their preparation. The new chemical compounds have the general formula: ##STR1## in which: R is a lower alkyl

Amino-aryl 1,24-triazines useful in the treatment of diverse pain

5-Bromo-N-(N.sup.1 -pyrrolidino-alkyl)-ortho-cresotamides having 2 to 5 carbon atoms in the alkyl moiety and therapeutically acceptable salts thereof, compositions containing such compounds useful as antitussives, and a method of suppressing of a cough in a host by administering an effective amount of such a compound with a pharmaceutically acceptable excipient. 5-Bromo-ortho-cresotamide may also be named 5-bromo-2-hydroxy-3-methyl-benzamide.

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Castres, France

Antoine Stenger