Other

Centre National De La Recherche Scientifique

Université De Nantes

Université Paris-Sud 11

Chu Nantes

Antoine Monsel

Karim Asehnoune

Marie-Pierre Fontaine-Aupart

Antoine Roquilly

Sandrine Lecart

The present invention relates to an in vitro method for diagnosing the infectious state of an individual on the basis of a sample of white corpuscles arising from a biological specimen taken from an organ potentially infected by a pathogenic microorganism of said individual, comprising at least the following two steps: i) measuring the mean cellular intensity of the autofluorescence of said sample, and ii) comparing the intensity measured in step i) with a control value, so as to determine the infectious state of said individual. The diagnostic method of the invention uses a routine optical material making it possible to work in wavelength regions which are compatible with the cellular autofluorescence, and thus constitutes a rapid, reliable and inexpensive aid for the diagnosis or monitoring of an infection in an individual.

Cytological method using the auto fluorescence of white corpuscles for the early diagnosis and the monitoring of infections

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Chatillon, France

Antoine Monsel