Centre National De La Recherche Scientifique

Institut National De La Sante Et De La Recherche Medicale

Université Nice Sophia Antipolis

Université Cote D'azur

Inserm

Antoine Millet

Rachid Benhida

Stephane Rocchi

Robert Ballotti

Cyril Ronco

Magali Plaisant

Stéphane Rocchi

The present invention relates to compound of general formula (I) Ris selected from H, aryl and alkyl, Ris selected from H, alkyl, aryl and CO&#x2014;R; Ris selected from H, halogen, alkyl, alkenyl, alkynyl, aryl, NHR, NRR, ORand SR; Ris selected from (C-C) alkyl, (C-C) alkenyl, (C-C) alkynyl and (C-C) aryl, Rrepresents H, R, aryl, OH, OR, O-aryl, SH, SR, S-aryl, CN, NO, CF, COOR, SONRR, CONRR, NH, NHR, NH-aryl, NRR, NHCORor aminoacyl; Ris alkyl optionally substituted with halogen, OH, SH, NH, O-alkyl, S-alkyl, NH-alkyl or NH-di(alkyl); Rand Ridentical or different are H or alkyl optionally substituted with halogen, OH, SH, NH, O-alkyl, S-alkyl, NH-alkyl or NH-di (alkyl), their pharmaceutically acceptable salts and/or isomers, tautomers, solvates or isotopic variations thereof. The compounds are useful for the treatment of cancers. 

Substituted hydrophobic benzene sulfonamide thiazole compounds for use in treating cancer

Growing community of inventors

Nice, France

Antoine Millet