Ifp Energies Nouvelles

Proteus Gmbh

Centre National De La Recherche Scientifique

Centre National De La Recherche Scientifique-cnrs

Antoine Margeot

Christophe Ullmann

Sebastien Fort

Sylvie Armand

Celine Ayrinhac

Cecile Persillon

Olivier Bonzom

Maud Petit

Stephanie Pradeau

Hugues Mathis

Lionel Rousseau

Françoise Le Roux

Frédérique Bidard-Michelot

Marine Lenon

Nicolas Lopes Ferreira

Laurent Fourage

Senta Blanquet

Yves Benoit

Laetitia Chan Ho Tong

Nicolas Lopes-Ferreira

Cécile Persillon

Céline Cohen

Francoise Le Roux

Frederique Bidard-Michelot

Céline Ayrinhac

Stéphanie Pradeau

Sébastien Fort

The invention relates to a method for producing a protein in a filamentous fungus cell, comprising the overexpression of the TrAZF1 gene or of one of the variants thereof in said cell.

Mutant strains of

The present invention relates to the expression and optimization of enzymes involved in the breakdown of lignocellulosic biomass. Disclosed are variants of the exoglucanase 1 of, as well as the use of said variants with improved efficiency in methods for breaking down cellulose and for producing biofuel.

Variants of exoglucanases having improved activity and uses thereof

The present invention relates to the expression and optimisation of enzymes involved in the breakdown of lignocellulosic biomass. The present invention relates to variants of the exoglucanase 2 of, as well as to the use of said variants with improved efficiency in methods for breaking down cellulose and for producing biofuel.

The present invention relates to astrain which is hyper-producing and which has enhanced &#x3b2;-glucosidase activity, as well as the use of said strain.

Hyper-producing trichoderma reesei strain having an enhanced beta-glucosidase activity

Disclosed are variants ofendoglucanase I, and methods for using such variants to break down cellulose and produce biofuel.

Endoglucanase variants having improved activity, and uses of same

The present invention relates to the expression and optimization of enzymes involved in the breakdown of lignocellulosic biomass. The present invention relates more specifically to variants ofendoglucanase II, and the use of said variants having an improved performance in methods of breaking down cellulose and producing biofuel.

The invention relates to a polypeptide which has enhanced beta-glucosidase activity at a temperature of between about 30&#xb0; C. and about 35&#xb0; C.

Polypetide with enhanced beta-glucosidase activity at low temperature

The present invention relates to the expression and optimization of enzymes involved in lignocellulosic biomass decomposition. The present invention relates more particularly to beta-glucosidase variants comprising at least one modification among the amino acids located at positions 225, 238, 240 and 241, according to the numbering in SEQ ID No. 2 ofbeta-glucosidase, and also relates to the use of said variants having improved effectiveness in methods for cellulose decomposition and biofuel production.

Beta-glucosidase variants having improved activity, and uses thereof

The present invention describes the use of a genetically improvedstrain allowing to limit microbiological contaminations during an industrial process. The genetic strain improvement allows the latter to overexpress an extracellular protein having known antimicrobial properties and compatible with the secretory system of strains of fungi such as. This modified strain can be used to produce the cellulolytic and/or hemicellulolytic enzymes used in a method of producing ethanol from cellulosic or lignocellulosic materials referred to as 'second generation' materials.

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Paris, France

Antoine Margeot