Dyax Corporation

Takeda Pharmaceutical Company Limited

Anthony Williams

Robert Charles Ladner

Arthur Charles Ley

Shirish Hirani

Luigi Bergamaschini

Daniel J Sexton

Andrew Nixon

Maria Grazia De Simoni

Qi-Long Wu

Maria Grazia Simoni

Henry Blair

Thomas Beck

Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.

Prevention and reduction of blood loss

Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.

Kallikrein-inhibitor therapies

The invention features hK1 binding polypeptides as well as compositions comprising such polypeptides and methods of making and using such polypeptides.

HK1-binding proteins

Antibodies that bind hK-1

Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g., coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.

Growing community of inventors

Melrose, MA, United States of America

Anthony Williams