Illumina Corporation

Irori

Anthony W Czarnik

Mark S Chee

John R Stuelpnagel

Steven Mark Barnard

Xiao-Yi Xiao

Chanfeng Zhao

Bahram Ghaffarzadeh Kermani

John E Lillig

Todd Alan Dickinson

Gary S David

Zahra Parandoosh

Shawn O Meade

Gordon W Hudson

James Bierle

Robert Neeper

The invention relates to compositions and methods for multiplex decoding of microsphere array sensors.

Multiplex decoding of array sensors with microspheres

The invention relates to compositions and methods for decoding microsphere array sensors.

Method of making and decoding of array sensors with microspheres

Decoding of array sensors with microspheres

The invention relates methods of improving signal detection from an array and methods for background subtraction in an array. The invention provides for novel array compositions including arrays with wells with different shapes, or surfaces coated with reflective or selectively absorptive coatings. In addition, the array include a signal transducer element.

Array compositions for improved signal detection

Methods for irradiation induced graft polymerization of a monomers, such as styrenes, onto fluoropolymers are provided. The methods, which involve either the use of acids, preferably mineral acids, or creating a rough surface on the fluoropolymer, provide higher levels of grafting of the copolymer than grafting in the absence of the acid or of the rough surface on the fluoropolymer. Also provided are grafted copolymers produced by the methods. Methods for increasing the performance of solid phase assays, such as scintillation proximity assays, are also provided.

Radiation-grafted solid supports for chemical synthesis

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San Diego, CA, United States of America

Anthony W Czarnik