Battelle Memorial Institute

Gene-trak Systems

Battelle, Centre De Recherche De Geneve

Serono Diagnostic Partners

Anthony Ringrose

Claus Dahne

John F Place

Ranald M Sutherland

Device for mixing at least one aqueous fluid substance

A container for determining antibodies or antigens in a biological liquid by the formation of specific antibody-antigen complexes, in which one partner element is initially associated with suspended magnetic particles that are subsequently regrouped against a collecting area of a first side wall of the container when the container is positioned within a magnetic field that extends through that area of the side wall. To prevent the particles from sliding down when the magnetic field is eliminated and to allow effective pipetting, the lower part of the side wall is adjacent to a planar surface formed at an obtuse angle to said side wall and tangent to a concave bottom surface that is itself tangent to a second side wall of the container located opposite to the first side wall.

Container for adding antibodies or antigens to a biological liquid

An apparatus responsive to optical changes in a waveguide when the latter is contacted with an analyte capable of reacting with a specific reactant thereto attached to the surface of said guide involves, for containing the analyte, an interchangeable round bottomed cuvette temporarily held by a suitably shaped carrier in working relationship with the optical components of the apparatus, this arrangement ensuring a correct optical orientation thereof relative to said component whatever the exact positioning of the cuvette.

Analytical assembly usable in apparatuses for optically determining

A cigarette is provided with an automatic valve responsive to the moisture content of the smoke for controlling induction of air into the smoke thereby compensating for the increase of nicotine concentration as the cigarette smokes down. The valve utilizes a bilamellar strip having sides of different hydrophilic character and distorting as a result of elongation of the more hydrophilic side.

Cigarette with automatic ventilation valve

The viscosity of a fluid material, e.g. a synthetic-resin composition, or the coagulation of blood or plasma monitored by placing a quantity of the fluid substance on a support, directing a beam of light upon the sample, detecting reflected light from the sample and vibrating the support at a given frequency and amplitude to disturb its surface. The reflected light detected is a function of the viscosity or the degree of coagulation.

Growing community of inventors

Chene Bougeries, Switzerland

Anthony Ringrose