Johnson & Johnson Consumer Inc.

Anthony R Geonnotti

Robert J Gambogi

Aliaksandr Zhuk

Jennifer Li

Latrisha Petersen

Patricia L Golas

Michael C Giano

Dara Miller

Benjamin Serbiak

Tara Fourre

Helle Wittorff

Nikoleta Batchvarova

Heidi Ziegler Bruun

Dorthe Shackinger Boesen

Nicole Comito

Provided are methods and compositions suitable for treating acne, disrupting a biofilm, and/or killing bacteria contained in a biofilm. Certain methods comprise applying to a surface having a biofilm a composition comprising a first alpha hydroxy acid, a second alpha hydroxy acid, and a polyhydroxy acid.

Methods suitable for disrupting a biofilm, and/or killing bacteria contained in a biofilm

Provided are methods and compositions suitable for treating acne, disrupting a biofilm, and/or killing bacteria contained in a biofilm. Certain methods comprise contacting skin in need of such treatment with a composition comprising two alpha hydroxy acids and a polyhydroxy acid.

Methods suitable for the treatment of acne

Provided are compositions suitable for treating acne, disrupting a biofilm, and/or killing bacteria contained in a biofilm. Certain compositions comprise

Methods and compositions suitable for the treatment of acne

Provided are compounds described by the Formula I: wherein: Ris a linear or branched, saturated or unsaturated aliphatic group having from 5 to 22 carbon atoms; Ris selected from the group consisting of the functional groups: and salts thereof; n is from 0 to 4; and Ris a linear or branched, saturated or unsaturated aliphatic group having from 1 to 6 carbon atoms. Also provided are compositions comprising, and methods of use of, the compounds of the present invention.

Amino acid derivatives and their uses

Provided are methods of providing at least one oral care benefit by introducing a tablet into the oral cavity to generate a fluid and forcing at least a portion of fluid generated around the oral cavity, for example, by swishing, rinsing, washing, etc., to provide an oral care benefit.

Method of providing oral care benefits

Provided are compounds described by the Formula I: wherein: Ris a linear or branched, saturated or unsaturated aliphatic group having from 5 to 22 carbon atoms; Ris selected from the group consisting of the functional groups: and salts thererof; n is from 0 to 4; and Ris a linear or branched, saturated or unsaturated aliphatic group having from 1 to 6 carbon atoms. Also provided are compositions comprising, and methods of use of, the compounds of the present invention.

Provided are compositions comprising succinic acid, aconitic acid, and a carrier, wherein the succinic acid and aconitic acid are present in a ratio of from about 0.9:1 to about 40:1. Also provided are methods of disrupting a biofilm comprising applying to a surface having a biofilm a composition of the present invention.

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Princeton, NJ, United States of America

Anthony R Geonnotti