Ethicon, Gmbh

Ethicon Endo-surgery, Inc.

The General Hospital Corporation

Janssen Biotech, Inc.

Janssen Pharmaceuticals, Inc.

Anthony R DiUbaldi

Michael R Tracey

Stephen Wahlgren

Jason L Harris

Rex O Bare

Tamara Colette Baynham

Bradley Joseph Sargent

James Walden Voegele

Jeyakumar Subbaroyan

Frederick E Shelton, IV

Gregory J Bakos

Kevin L Houser

Mark S Ortiz

Taylor W Aronhalt

Mark S Zeiner

Peter A Krulevitch

Jeffrey Christopher Smith

Michael A Murray

David James Cagle

David N Plescia

Thomas Edward Albrecht

Michael Scott Hutchinson

Lee M Kaplan

Martin Nohilly

Nicholas Stylopoulos

Steven M Vesole

John Young

Douglas B Johns

Kathryn Kukulka

Francesco N Albertini

Michael William Ammerman

Theodore L Stephens

Jacob Crabtree

Michael Freeman

James Fleming

Smart pill bottle caps are provided. In general, a smart pill bottle cap can include a housing. The housing can include a sensor that is configured to monitor one or more characteristics of a pill bottle to which the housing is attached and can include a communication mechanism configured to communicate the one or more characteristics of the pill bottle to an external device. The communicated characteristic(s) of the pill bottle can be used to track usage of pills in the pill bottle, such as a date and time of when a pill was taken and/or a number of pills remaining in the pill bottle. A smart pill bottle cap can also be configured to engage a secondary, standard pill bottle cap that is used with a standard pill bottle.

Smart pill bottle caps

In general, drug administration devices that communicate with surgical hubs and methods of using drug administration devices that communicate with surgical hubs are provided. In one aspect, a surgical system is provided that in one embodiment includes a drug administration device configured to administer a drug to a patient during performance of a surgical procedure. The drug administration device includes a first communications interface and a first processor configured to cause the first communications interface to transmit data regarding operation of the drug administration device during the performance of the surgical procedure. The surgical system also includes a surgical hub including a second processor and a second communications interface. The second communications interface is configured to receive the transmitted data from the first communications interface during the performance of the surgical procedure.

Drug administration devices that communicate with surgical hubs

A medical patch having a multi-piece bottom liner including a central liner sequentially removable independently of two outer perimeter liners. The multi-piece liner covering two adhesives of different peel force. Removal of the central liner exposes a first temporary/repositionable adhesive. Once properly positioned, the outer perimeter liners are removed to expose a second stronger adhesive. A foam cushioning layer is disposed beneath and extends beyond a footprint of every printed circuit board to prevent skin irritation. The medical patch may be designed specifically for stimulation of the sacral (S3 foramen) spinal nerve without the use of a separate mechanical placement tool or assistance by another.

Transdermal medical patch

Methods and devices are provided for activating brown adipose tissue (BAT). Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss. In one embodiment, a medical device is provided that activates BAT by electrically stimulating nerves that activate the BAT and/or electrically stimulating brown adipocytes directly, thereby increasing thermogenesis in the BAT and inducing weight loss through energy expenditure.

Methods and devices for activating brown adipose tissue using electrical energy

A method and associated stimulation device for ensuring firing of an action potential in an intended physiological target activated by a stimulus pulse generated by an electrode of a non-invasive surface based stimulation device irrespective of skin-to-electrode impedance by: (i) increasing internal impedance of the stimulation device so as to widen a Chronaxie time period thereby ensuring firing of the action potential of the intended physiological target irrespective of the skin-to-electrode impedance; and/or (ii) generating a stimulation waveform that optimizes a non-zero average current (e.g., non-zero slope of the envelope of the stimulation waveform) during preferably substantially the entire current decay of the stimulus pulse.

Optimizing the stimulus current in a surface based stimulation device

A device for providing transdermal electrical stimulation at an adjustable position on a head. The device including a supporting member economically shaped and configured to be fixedly supported about an anatomical body part; the supporting member being adjustably positionable in only two directions substantially perpendicular to one another. No electrical stimulation is provided by the supporting member. Alternatively, the device includes at least one pair of electrodes for producing the transdermal electrical stimulation to the head. The electrodes are mounted to a securing member shaped and configured to be releasably securable only about a plurality of strands of hair at a predetermined fixed orientation without being secured about any anatomical body part.

Device for providing transdermal electrical stimulation at an adjustable position on a head

Self-positioning of at least a portion of a transdermal electrical stimulation patch within a target area (e.g., supraclavicular fossa region) of a human body to activate a depot of brown adipose tissue therein. An electric field is generated using the electrical stimulation patch to activate the brown adipose tissue within the supraclavicular fossa region of the body. The patch is self-positioned using one or more anatomical points (e.g., anatomical landmarks and/or anatomical features) or markings on the body. Brown adipose tissue may also be activated by applying an electrical signal to a body piercing partially implanted proximate a target area in which the tissue is disposed.

Device and method for self-positioning of a stimulation device to activate brown adipose tissue depot in a supraclavicular fossa region

A medial treatment device for treating at least first and second medical conditions is provided, as well as a method for using the same. The medical treatment device includes a stimulation device for treating the first medical condition with electrical stimulation, and an implantable mesh adapted for implantation within the patient to treat the second medical condition. The implantable mesh has a plurality of incorporated electrically conductive elements adapted to conduct electrical stimulation from the stimulation device to a position closer to a predetermined body part the stimulation of which at least partially treats the first medical condition.

Conductive mesh for neurostimulation

A method for stimulating a predetermined body part such as a nerve using a stimulation device including an external non-implantable transmitting device powered by a power source and generating an electrical waveform signal. A surface electrode applies the generated electrical waveform signal transcutaneously. An implantable piezoelectric element receives the applied electrical waveform signal generated transcutaneously and, in turn, causes mechanical deformation resulting in mechanical vibration of the implantable piezoelectric element sufficient to stimulate the predetermined body part. The electrical waveform signal may be either a high frequency continuous waveform or high frequency burst packets.

Piezoelectric stimulation device

A system and method for stimulating a nerve, wherein the system includes a first waveform generator adapted to generate a first waveform having a frequency capable of stimulating a predetermined nerve of the mammal, a second waveform generator adapted to generate a carrier waveform having a frequency capable of passing through tissue of the mammal, a modulation device electrically coupled to the first and second waveform generators and adapted to modulate the first and carrier waveforms to create a modulated waveform, and an electrode electrically coupled to the modulation device and positioned substantially adjacent to skin of the mammal, and adapted to apply the modulated waveform thereto.

System and method for nerve stimulation

An Implantable Pulse Generator (IPG) includes a surgically implantable housing, a battery, a first waveform generator, a second waveform generator, a modulator, and electrodes. The IPG produces a pulse envelope, a carrier waveform, and a modulated waveform. The pulse envelope is a low frequency waveform with specific pulse width, amplitude and shape to selectively stimulate a target nerve or body part. The carrier waveform is a high frequency waveform with properties such as amplitude, frequency and the like chosen so as to overcome tissue impedance and the stimulation threshold of the target nerve. The modulated waveform is the waveform obtained by modulating the carrier waveform by the pulse envelope.

Implantable pulse generators and methods for selective nerve stimulation

A selective nerve stimulation patch includes a substrate having a top surface and a bottom surface, integrated components overlying the top surface of the substrate and being electrically interconnected with one another for generating at least one nerve stimulating signal, electrodes integrated into the substrate and exposed at the bottom surface thereof for applying the at least one nerve stimulating signal to a target nerve, a waterproof, breathable cover overlying the substrate and the integrated components, and a support flange surrounding the substrate and coupling the cover and the substrate together. The support flange has a top surface that slopes downwardly toward an outer perimeter thereof, and at least a portion of the cover conforms to the sloping top surface of the support flange. In one embodiment, the patch generates a high frequency waveform with properties such as amplitude, frequency and the like chosen so as to overcome tissue impedance and the stimulation threshold of the target nerve. The modulated waveform is the waveform obtained by modulating the carrier waveform by a pulse envelope.

Nerve stimulation patches and methods for stimulating selected nerves

A system for stimulating a nerve or nerves in a patient includes an electrode patch having an array of equally spaced concentric electrodes each having a central cathode and a concentrically surrounding anode. The electrode array patch is used to determine the location of the nerve or nerves to be stimulated by electrical pulses. Once the location of the nerve is determined, a concentric electrode patch having a central cathode and a concentrically surrounding anode is positioned at the optimal location on the patient's skin to effect neurostimulation. The concentric electrode patch may be removably affixed to the patient's skin by adhesive or magnets.

Electrode patch and method for neurostimulation

A nerve stimulation device includes a first waveform generator adapted to generate a first waveform having a first frequency capable of stimulating nerves within a dermatome, a second waveform generator adapted to generate a first carrier waveform having a second frequency capable of passing through tissue of a mammal, and a third waveform generator adapted to generate a second carrier waveform having a third frequency different than the second frequency and being capable of passing through the tissue of the mammal. The device includes a modulator electrically coupled to the first, second and third waveform generators and adapted to modulate the first waveform, the first carrier waveform, and the second carrier waveform to generate a modulated signal package capable of stimulating the nerves at different depths within the dermatome. The device also has an electrode electrically coupled to the modulator for applying the modulated waveform to the dermatomic region.

Dermatome stimulation devices and methods

A device and method is provided for transdermally stimulating selected body parts of a mammal. The device includes a first waveform generator adapted to generate a first waveform having a first frequency capable of stimulating a first predetermined body part, a second waveform generator adapted to generate a carrier waveform having a second frequency capable of passing through tissue of the mammal, and a third waveform generator adapted to generate a third waveform having a third frequency different from and out of phase with that of the first waveform, and capable of stimulating a second predetermined body part. The device further includes a modulation device electrically coupled to the first, second and third waveform generators and adapted to modulate the carrier, first, and third waveforms to create a modulated signal package, and a first electrode electrically coupled to the modulation device and positioned substantially adjacent to the skin of the mammal, and adapted to apply the modulated signal package thereto.

Growing community of inventors

Jackson, NJ, United States of America

Anthony R DiUbaldi