Sanofi

Sanofi-a Ventis Deutschland Gmbh

Medmix Switzerland Ag

Elekta Ab

Elektra Ab (publ)

Anthony Paul Morris

Matthew Meredith Jones

Samuel Steel

Joseph Butler

William Marsh

Paul Richard Draper

David Aubrey Plumptre

Stephen Francis Gilmore

Robert F Veasey

Richard James Vincent Avery

William Geoffrey Arthur Marsh

Oliver Charles Gazeley

Barry Yates

Craig Ashley Mason

Michael Schabbach

Aidan Michael O'Hare

Felix Kramer

Richard James Thomas

Beat Wyss

Daniel Edward Clark

Ronald Antony Smith

Brian Charles Molyneux

Aled Meredydd James

Christian Rehbein

Philipp Müller

Michael Jugl

Stefan Blancke

Mark Digby Teucher

David Moore

Paul Roger Griffin

James Anthony West

James Robert Coop

Daniel David Higgins

Philipp Muller

Mike Cameron Bainton

Ralph Donald Quentin Collings

Neal Alexander Blundred

Alexander John Baker

Malcolm Stanley Boyd

John David Cross

Timothy Lewis Sharpe

Sarah Witheford

Daniel Paul Jenkins

Aidan Michael O'hare

Axel Teucher

Daniel Thomas De Sausmarez Lintell

David Richard Mercer

George Cave

Gertrud Blei

Mario Bock

Markus Ploch

Theresa Kunz

Sophie Louise Sladen

Andrew Gordon Wallace

Alexander James Woolley

Georgina Millington

Gavin Newman

Denny Lustosa Horn

Richard Paul Gledhill

William Geoffrey Arthur Marsch

Oliver Benjamin Brown

James Lewis Gareth

Andrew Mark Lindsay

Samuel Keir Steel

Robert Frederick Veasey

Dave Aubrey Plumptre

The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.

Medicament injection device

An electronic system for a drug delivery device comprising a dose setting and drive mechanism with a first member, wherein the first member performs a specific movement relative to a second member during a dose delivery operation. The electronic system comprises a first switch configured to be activated by a pre-defined user operation, wherein the pre-defined user operation includes a user operation that is expected in conjunction with dose delivery operation, a second switch for indicating the specific movement, and a sensor arrangement for a motion sensor system for providing position data that allows to distinguish between different positions of the first member relative to the second member.

Electronic system and method for determining failure of a second switch in a drug delivery device

An autoinjector includes a housing and a drive chassis arranged linearly moveable within the housing. The drive chassis includes a dispensing limb and a trigger limb. The trigger limb and the dispensing limb are arranged in parallel to one another and are connected to one another at a respective distal end of the dispensing limb and the trigger limb.

Autoinjector

A sensor device removably attachable to a drug delivery device includes a sensing arrangement arranged within the sensor device and circuitry configured to process signals provided by the sensing arrangement. The sensing arrangement is configured such that, when the sensor device is attached to the drug delivery device, the sensing arrangement is operable to read encoded information present on a rotatable component internal to the drug delivery device and that is able to be sensed through a window or aperture of the drug delivery device, and is operable to sense through the window or aperture at least a part of a drive mechanism of the drug delivery device. The circuitry is configured to determine information relating to a set dose, and to determine information relating to whether the drug delivery device is in a dose setting mode or whether the device is in a dose delivery mode.

Sensor device removably attachable to a drug delivery device

The disclosure relates to an injection device for setting and injecting pre-set or user-selectable doses of a medicament, the injection device comprising an elongated housing defining a longitudinal direction and configured to accommodate a cartridge containing the medicament, and a detector arrangement operable to detect a relative movement between a first element and a second element. The first element is subject to a first movement relative to the second element along a first longitudinal direction for setting of a dose, the first element is subject to a second movement relative to the second element along a second longitudinal direction for dispensing of the dose, one of the first movement and the second movement is a helical movement, and the other one of the first movement and the second movement is a sliding movement in the longitudinal direction. The second element comprises at least one reference element fixed to the second element.

Injection device and detector arrangement

An autoinjector basically includes a housing, a pre-filled syringe, a drive chassis, and a needle guard. The pre-filled syringe is mounted in the housing. The drive chassis is configured to move a plunger in the pre-filled syringe to dispense medicament via an urging force from a drive spring. The needle guard is moveable in the housing between a storage state, a dispensing state, and a lock-out state. The needle guard is biased towards an extended position by a lock-out spring. The needle guard selectively engages the housing to establish a frontmost position of the needle guard in the storage state, and an offset position of the needle guard in the lock-out state. The offset position is axially offset from the frontmost position in the distal direction.

A button for a drug delivery device with a reduced operating loudness includes a plate-like button body forming a touch surface, wherein the plate-like button body is coupled by an axial supporting member to a noise-generating interface of the drug delivery device and movable into a longitudinal direction of the drug delivery device, wherein the plate-like button body includes a material composite with at least one first component consisting of a first material and at least one second component consisting of a second material different from the first material, wherein the at least one first component and the at least one second component are coupled via at least one coupling plane that is at least sectionwise slanted or perpendicular to the longitudinal direction. Further, the disclosure describes a button assembly for a drug delivery device which is shock resistant.

Button and button assembly for a drug delivery device

A drive train for a wind-up injection device is described. The drive train includes a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle, a rotationally driveable expelling mechanism adapted to expel the liquid drug, and a clutch element coupled with the torsional energy storage via the rotatable element and including a ratchet for maintaining the rotatable element at one of a number of discrete angular positions against the torque of the torsional energy storage. The clutch element is adapted to transmit the torque from the user handle to the torsional energy storage, or alternatively from the torsional energy storage to the expelling mechanism. The ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage. The drive train is adapted to dampen torque peaks visco-elastically and/or visco-frictionally.

Drive train for dial of a torsion-spring assisted wind-up injection device

A handheld injection device includes a housing containing a cartridge, a dose setting means being operable in a first direction to set a desired dose to be dispensed, a piston rod being adapted to cooperate with a piston so as to cause a set dose to be injected from the cartridge, and a first clicker component, which is largely rotationally constrained to the housing, and a second clicker component, which is rotatable relative to the housing during dose dispensing. The clicker components are adapted to contact each other only at the end of dispensing of a set dose to thereby provide an audible and/or tactile first feedback to a user. The first clicker component is displaceable relative to the housing between a proximal dose setting position and a distal dose dispensing position.

Injection device

The invention relates to an arrangement for detecting a position of a plunger () relative to a bung () in a drug cartridge (), comprising a proximity sensor () located close to a distal end () of the plunger () facing the bung () and aligned to receive light reflected by the bung ().

Arrangement for detecting a position of a plunger

Medicament injection device with rotary encoder

A sensor device is removably attachable to a drug delivery device. The sensor device comprises an array of optical sensors arranged within the sensor device such that, when the sensor device is attached to the drug delivery device, which has a first movable element configured to move along a path parallel to the longitudinal axis of the drug delivery device, each optical sensor is operable to detect light received at different locations along the path and to output a signal indicative of an amount of detected light. Circuitry is configured to receive the signals output from the optical sensors and, based on the received signals, determine information associated with a location along the path of the first movable element.

Growing community of inventors

Coventry, United Kingdom

Anthony Paul Morris