Pharmacia Ab

Anthony N De Belder

Leif G Ahrgren

Tomas Malson

Thomas Malson

Method of preventing adhesion between body tissues, means for preventing

A new method for preparation of sulfated polysaccharides by means of pyridine-chlorosulfonic acid reagents. The polysaccharide is before sulfation treated with a reducing agent, e.g. sodium borohydride.

Method for preparation of sulfated polysaccharides by treating the

A shaped article based upon cross-linked, possibly derivatized hyaluronic acid or a salt thereof is characterized in that it has a dry matter content of at least 65 percent by weight and a tensile strength of at least 2 N/cm.sup.2. The shaped article may be prepared by pressure-drying or freeze-drying a corresponding hyaluronic acid gel.

Shaped article and processes for its preparation

The invention relates to a new polymer containing quarternary amino group based on dextran or cross-linked dextran. The quarternary amino groups are of the formula ##STR1## where R.sub.1, R.sub.2 and R.sub.3, which may be identical or different, are lower alkyl groups of 1-5 carbon atoms or lower hydroxyalkyl groups of 2-5 carbon atoms and 1-2 hydroxy groups. At most one atom other than carbon and hydrogen is bound to the same carbon atom in the hydroxy alkyl group.

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Upsala, Sweden

Anthony N De Belder