Carefusion 2200, Inc.

Takeda Pharmaceutical Company Limited

Uti Limited Partnership

Baxalta Gmbh

Anthony Martin Looper

Jeffrey Schmitt

John A Krueger

Daniel Edward Roush

Madeleine Clare Gibson

Seth Dale Jones

Mark David Schweiss

Stefan Holzner

Jessica Chung

Tejas Dhyani

Michelle Shah

David M Carpenter

Erin-Anne Lemieux

Robert F Leonard

Brooke Skora

Alain Tremblay

David Booth

Joseph Tommasini

Monica Sanders

Griffin Strole

David J Booth

A catheter for use in treating pleural diseases, such as pleural effusions and pneumothorax, includes a tip portion that is configured to irritate the pleura when the catheter is inserted in the pleural cavity, thereby initiating mechanical pleurodesis. The tip portion has a substantially rough configuration and may include one or more protrusions that contact the pleura when the catheter is in use, thereby irritating the layers. This irritation causes the creation of fibrous adhesions between the parietal and visceral layers that close off the pleural cavity and prevent further fluid and/or air accumulations that occur as a result of pleural diseases.

Catheter design for use in treating pleural diseases

A device is provided for pooling a fluid from a container unit having at least one container, and includes an inlet port having at least one inlet channel configured for receiving the fluid or ambient air, and an outlet port having at least one outlet channel configured for delivering the fluid to an attachment. Both inlet and outlet ports are disposed on the device. A cavity is provided for accommodating insertion of the container unit for pooling the fluid from the at least one container. At least one spike is disposed in the cavity and configured for puncturing a stopper of the at least one container when the container unit transitions from an upper position to a lower position.

Pooling device for single or multiple medical containers

A catheter for use in treating pleura diseases, such as pleural effusions and pneumothorax, includes a tip portion that is configured to irritate the pleura when the catheter is inserted in the pleural cavity, thereby initiating mechanical pleurodesis. The tip portion has a substantially rough configuration and may include one or more protrusions that contact the pleura when the catheter is in use, thereby irritating the layers. This irritation causes the creation of fibrous adhesions between the parietal and visceral layers that close off the pleural cavity and prevent further fluid and/or air accumulations that occur as a result of pleural diseases.

The present invention provides methods of treating pleural effusion in a subject, comprising removing fluid from the pleural space at an increased frequency, as compared to previous methods.

Method of treating pleural effusion

A drug eluting catheter includes an active agent, such as a drug or chemical substance, which is integrated with the catheter and allows variable dosing of the agent for elution to the patient's body. The catheter includes a dosing region and graduated markings or is associated with a measurement device that includes graduated markings that correspond to a range of dose of the active agent associated with the catheter. By removing or masking an undesired dosing region prior to administration, a user may vary the dosage to suit a patient's needs.

Catheter allowing variable dosing of an active agent

A laparoscopic surgical device is provided, including a ratchet mechanism. The ratchet mechanism includes a single button or lever that may be used to release or defeat a ratchet engagement.

Surgical device

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Lake Zurich, IL, United States of America

Anthony Martin Looper