Oxford Nanopore Technologies Limited

Anthony Jones

Jonathan Upsdell

Jean Thomassin

Andre Julien

Richard Ullyott

Sensor device

A piston head for a syringe pump comprises a barrier portion () for driving fluid through a syringe pump barrel (), wherein a peripheral section () of the barrier portion () is shaped to seal against the syringe pump barrel (); and a re-silent member () arranged to resist deformation of the shaped peripheral section () of the barrier portion ().

Piston seal

A pump for use in low-profile applications comprises a barrel for holding fluid; and a piston that converts a rotational driving force into a longitudinal driving motion within the barrel. The pump provides space saving advantages by reducing the need for external equipment and mechanisms around the pump for providing actuation or moving the actuating mechanism.

Pump

A one-way valve, comprises a valve housing; a valve member provided within the valve housing, the valve member being operative to open and close the valve and comprising a diaphragm with a central orifice to allow fluid to pass from one side of the diaphragm to the other; a valve inlet provided on a first side of the diaphragm; and a valve outlet provided on a second side of the diaphragm; wherein the configuration of the diaphragm and the valve housing biases the diaphragm to seal the inlet at rest.

One-way valve

An analysis apparatus for performing biochemical analysis of a sample using nanopores comprises: a sensor device that that supports plural nanopores, reservoirs holding material for performing the analysis; a fluidics system; and plural containers for receiving respective samples, all arranged in a cartridge that is removably attachable to an electronics unit arranged to generate drive signals to perform signal processing circuit to generate output data representing the results of the analysis. The fluidics system supplies samples selectively from the containers to the sensor device using a rotary valve. In one valve, a stator defines a plurality of first ports arranged around the rotational axis and a collection chamber extending in around the axis of rotation in communication with a second port. A rotor provides a passage extending between the collection chamber and a position in communication with any one of the plurality of first ports. In another valve a stator defining a plurality of first ports in an annular surface facing the rotational axis, and a rotor is mounted inside a liner arranged between the annular surface of the stator and a facing annular surface of the rotor. The liner has a greater compliance than the rotor and stator to facilitate sealing.

Biochemical analysis apparatus and rotary valve

An analysis apparatus for performing biochemical analysis of a sample using nanopores comprises: a sensor device that supports plural nanopores, reservoirs holding material for performing the analysis; a fluidics system; and plural containers for receiving respective samples, all arranged in a cartridge that is removably attachable to an electronics unit arranged to generate drive signals to perform signal processing circuit to generate output data representing the results of the analysis. The fluidics system supplies samples selectively from the containers to the sensor device using a rotary valve.

Growing community of inventors

Oxford, United Kingdom

Anthony Jones