Resmed Limited

The Brain Protection Company Pty Ltd

Resmed Pty Ltd

Redmed Limited

Anthony John Ujhazy

Glenn Richards

Jonathan Caldwell Wright

Zoran Milijasevic

David Stephen Celermajer

Michael Berthon-Jones

Klaus Henry Schindhelm

Mark David Buckley

Robert Douglas

David John Bassin

Johnathon Choi

Alison Mary Hansford

Michael P Wallace

Gregory Newton Brewer

Jarred Shein

Joanne Elizabeth Drew

Mark Carnegie

Mike Wallace

A device () for altering blood flow characteristics in a vessel (), the device () comprising: a cuff () configured to be surgically positioned around a portion of the vessel (); a first pad () located on an internal wall of the cuff (), wherein the pad (): locally reduces a cross-sectional area of a passageway () extending through the cuff () and/or defines a passageway () within the cuff () which is non-linear.

Device and method for altering blood flow characteristics in a vessel

Devices, systems, and methods for combinatorial treatment of a condition with an implantable damping device and therapeutic agent (e.g., drug) are disclosed herein. Methods for treating one or more effects of the condition, such as a neurological condition, include providing the implantable damping device and at least one other therapy, such as a therapeutic agent, that treats the condition to the patient. The implantable damping device includes a flexible damping member and an abating substance and can be placed in apposition with a blood vessel. The flexible damping member forms a generally tubular structure having an inner and an outer surface, the inner surface formed of a sidewall having a partially deformable portion. The abating substance is disposed within the partially deformable portion and moves longitudinally and/or radially within the partially deformable portion in response to pulsatile blood flow.

Combinatorial therapies including implantable damping devices and therapeutic agents for treating a condition and associated systems and methods of use

Devices, systems, and methods for reducing stress on a blood vessel are disclosed herein. A damping device () configured in accordance with embodiments of the present technology can include an anchoring member () coupled to a flexible, compliant damping member () including a generally tubular sidewall having an outer surface (), an inner surface () defining a lumen configured to direct blood flow, a first end portion () and a second end portion (), and a damping region () between the first and second end portions (). The inner and outer surfaces () of the damping member () can be spaced apart by a distance that is greater at the damping region () than at either of the first or second end portions (). When blood flows through the damping member () during systole, the damping member () absorbs a portion of the pulsatile energy of the blood, thereby reducing a magnitude of the pulse pressure transmitted to a portion of the blood vessel distal to the damping device ().

Implantable damping devices for treating dementia and associated systems and methods of use

A method for controlling operation of a CPAP apparatus. The apparatus has a blower, a patient interface, an air delivery conduit for delivering air from the blower to the patient interface, a sensor for determining the pressure in the patient interface, and a control mechanism that causes air to be delivered at a desired pressure to the patient interface and that detects transitions between inhalation and exhalation of a respiratory cycle of a patient in order to synchronise the blower output with the patient's efforts. In one form the CPAP apparatus provides pressure in accordance with a bi-level waveform with at least one characterising parameter of the waveform being automatically adjusted in accordance with indications of sleep disordered breathing. The indications of sleep disordered breathing can be one or more of snoring, apnea, hypopnea, and flow limitation.

Mechanical ventilation in the presence of sleep disordered breathing

Methods and apparatus for assessing the condition of and treating patients for heart failure by the delivery of continuous positive airway pressure are disclosed. Treatment of obstruction due to reflex vocal cord closure often experienced by heart failure patients is distinguished from treatment of upper airway obstruction typically associated with Obstructive Sleep Disorder. Treatment may also be implemented by delivering synchronized cardiac pressure oscillations superimposed on a respiratory pressure level to provide assistance for the heart. Heart treatment pressure dose indicator may be calculated for prescribing and monitoring the delivery of treatment. The apparatus may also generate data to track heart failure condition that may be indicative of the degree of severity of heart failure based upon breathing patterns to assist in the diagnosis and management of heart failure patients.

Methods and apparatus for heart failure treatment

A method for controlling operation of a CPAP apparatus. The apparatus has a blower, a patient interface, an air delivery conduit for delivering air from the blower to the patient interface, a sensor for determining the pressure in the patient interface, and a control mechanism that causes air to be delivered at a desired pressure to the patient interface and that detects transitions between inhalation and exhalation of a respiratory cycle of a patient in order to synchronize the blower output with the patient's efforts. In one form the CPAP apparatus provides pressure in accordance with a bi-level waveform with at least one characterizing parameter of the waveform being automatically adjusted in accordance with indications of sleep disordered breathing. The indications of sleep disordered breathing can be one or more of snoring, apnea, hypopnea, and flow limitation.

Devices, systems, and methods for reducing stress on a blood vessel are disclosed herein. A damping device configured in accordance with embodiments of the present technology can include an anchoring member coupled to a flexible, compliant damping member including a generally tubular sidewall having an outer surface, an inner surface defining a lumen configured to direct blood flow, a first end portion and a second end portion, and a damping region between the first and second end portions. The inner and outer surfaces of the damping member can be spaced apart by a distance greater at the damping region than at the first or second end portions. When blood flows through the damping member during systole, the damping member absorbs a portion of the pulsatile energy of the blood, thereby reducing a magnitude of the pulse pressure transmitted to a portion of the blood vessel distal to the damping device.

Methods and apparatus for detection and treatment of respiratory disorders using implanted devices are described. In one form, afferent nerves are electrically or electro-mechanically stimulated to increase the tone of upper airway muscles. Detection of respiratory disorders is carried out using electrodes implanted in sub-pectoral regions. Open and closed airway apneas are distinguished using a combination of acoustic detectors and electrical transducers.

Method and apparatus for detection and treatment of respiratory disorder by implantable device

A method for controlling operation of a CPAP apparatus. The apparatus has a blower, a patient interface, an air delivery conduit for delivering air from the blower to the patient interface, a sensor for determining the pressure in the patient interface, and a control mechanism that causes air to be delivered at a desired pressure to the patient interface and that detects transitions between inhalation and exhalation of a respiratory cycle of a patient in order to synchronise the blower output with the patient's efforts. In one form the CPAP apparatus provides pressure in accordance with a bi-level waveform with at least one characterizing parameter of the waveform being automatically adjusted in accordance with indications of sleep disordered breathing. The indications of sleep disordered breathing can be one or more of snoring, apnea, hypopnea, and flow limitation.

The invention features methods and apparatus for the treatment of asthma patients. A controlled supply of breathable air delivered to a patient interface or mask () is controlled for patient comfort to maintain a steady pressure level in a range 2 to 4 cm H2O to accommodate patient respiration. The breathable air is cleaned by a high efficiency particulate arresting filter () to remove allergens from the air supply. The apparatus may be programmed to automatically detect asthma-related symptoms such as an asthma attack by analyzing the respiratory flow of the patient. In response to the detection of such an attack, the apparatus may provide an audible warning or if configured with a treatment delivery module (A,B), the device may administer a therapeutically effective dose of a drug or substance, for example, a broncho-dilator, to alleviate the patient's breathing difficulty. Preferred mask designs allow for proper CO2 washout to accommodate the low pressures supplied to the mask and prevent asphyxia.

Methods and apparatus for supplying clean breathable gas

Methods and apparatus for assessing the condition of and treating patients for heart failure by the delivery of continuous positive airway pressure are disclosed. Treatment of obstruction due to reflex vocal cord closure often experienced by heart failure patients is distinguished from treatment of upper airway obstruction typically associated with Obstructive Sleep Disorder Treatment may also be implemented by delivering synchronized cardiac pressure oscillations superimposed on a respiratory pressure level to provide assistance for the heart. Heart treatment pressure dose indicator may be calculated for prescribing and monitoring the delivery of treatment. The apparatus may also generate data to track heart failure condition that may be indicative of the degree of severity of heart failure based upon breathing patterns to assist in the diagnosis and management of heart failure patients.

A method for controlling operation of a CPAP apparatus. The apparatus has a blower (), a patient interface (), an air delivery conduit () for delivering air from the blower () to the patient interface (), a sensor () for determining the pressure in the patient interface (), and a control mechanism () that causes air to be delivered at a desired pressure to the patient interface () and that detects transitions between inhalation and exhalation of a respiratory cycle of a patient in order to synchronise the blower output with the patient's efforts. In one form the CPAP apparatus provides pressure in accordance with a bi-level waveform with at least one characterising parameter of the waveform being automatically adjusted in accordance with indications of sleep disordered breathing. The indications of sleep disordered breathing can be one or more of snoring, apnea, hypopnea, and flow limitation.

Methods and apparatus for assessing the condition of and treating patients for stroke during the delivery of continuous positive airway pressure (CPAP) are disclosed. By determining central and obstructive apnea occurrences or the percentile of pressure delivered to the patient from patient airflow, stroke indicators may be calculated and analyzed to provide information on the type of stroke a patient has suffered and the degree of a patient's neuro-recovery. The apparatus may be programmed with a particular protocol intended to identify between alternative forms of CPAP treatment appropriate for the patient based upon an assessment of the patient's condition. The device can select and recommend between the various treatment forms, identify billing reimbursement codes and generate data to track patient response to stroke treatments.

Growing community of inventors

East Lindfield, Australia

Anthony John Ujhazy