Teraview Limited

Anthony J Fitzgerald

Bryan Edward Cole

Philip Francis Taday

Vincent Patrick Wallace

Imaging techniques of pharmaceutical preparations such as tablets are disclosed. The techniques combine the measurement of reflected/transmitted terahertz radiation originating from within the tablet and data analysis localized in frequency and time in order to enable a three dimensional image indicating composition to be obtained.

Imaging techniques and associated apparatus

A method of investigating a sample (breast tissue) (), the sample comprising at least a first material (normal breast tissue) in order to determine they presence of at least one further material (cancerous tissue), the method comprising the steps of: Irradiating the sample with electromagnetic radiation in the range from 25 GHz to 100 THz; Detecting radiation reflected from the sample; Determining a parameter related to the amplitude of the radiation, which is reflected from the sample, in the time domain; Analyzing the parameter derived in step (c) in order to determine if the sample further comprises the at least one further material wherein the irradiating and reflected radiation passes through a (z-cut quartz) window member () having a refractive index that falls between the refractive indices of the at least first and at least one further materials.

Image of sample using terahertz time domain spectroscopy in reflection mode to identify in a first material like normal breast tissue a second material like cancerous tissue by evaluating the phase change at the interface between the sample and a window like a quartz window, against which the sample is pressed

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Cambridgeshire, United Kingdom

Anthony J Fitzgerald