Pfizer Corporation

Anthony G Evans

Ian T Barnish

David A Cox

John C Danilewicz

Allan L Ham

Simon F Campbell

Colin Thomson

A series of 1-piperidinophthalazine derivatives as phosphodiesterase inhibitors and cardiac stimulants.

1-Piperidinophthalazines as cardiac stimulants

Novel substituted 1-phenyl-2-alkylamino-alkanols, 1-phenyl-2-alkylaminoalkanes and .alpha.-aminoalkyl phenyl ketones useful as heart stimulants are disclosed.

Phenyl-alkanolamine, alkylamine and .alpha.-aminoalkyl ketone

Novel substituted 1-phenyl-2-alkylamino-alkanols, 1-phenyl-2-alkylamino-alkanes and .alpha.-aminoalkyl phenyl ketones useful as heart stimulants are disclosed.

Phenyl-alkanolamine, alkylamine and alpha-aminoalkyl ketone derivatives

6,7-Dialkoxy-4-aminoquinazoline cardiac stimulants and synthetic methods for the preparation thereof.

4-Aminoquinazoline cardiac stimulants

Method of stimulating the heart employing substituted 1-phenyl-2-alkylamino-alkanols, 1-phenyl-2-alkylamino-alkanes and .alpha.-aminoalkyl phenyl ketones is disclosed.

Method of stimulating the heart employing ureido substituted

Certain novel 7-alkoxy-4-(N-[.omega.-(heteroaryl)alkyl]amino)quinazoline compounds, optionally bearing an alkyl or substituted alkyl group at the 2-position, an alkyl, benzyl, phenyl or alkoxyphenyl group on the 4-amino nitrogen atom, an alkyl or alkoxy group at the 5-position, and an alkyl alkoxy, hydroxy or amino group at the 6-position; and the acid-addition salts thereof. Compounds are cardiac stimulants.

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Westgate-on-Sea, United Kingdom

Anthony G Evans