International Technidyne Corporation

Instrumentation Laboratory Company

Thomas & Betts Corporation

International Techndyne Corporation

Anthony F Kuklo, Jr

James A Mawhirt

Catherine M Cimini

Donald A Foggia

Michael Gavin

Eduardo I Marcelino

Ming Huang

Gregory M Colella

Albert A Simone

Dimitri Shishkin

Henry D Huang

Maria Figueroa

Tadeusz Szostak

Donald W Allen

Peter J Sklenar

Christopher R Vander Wal

Gerald Feldman

Dimitri V Shishkin

Maria L Figueroa

An apparatus for measuring blood clotting time includes a blood clot detection instrument and a cuvette for use with the blood clot detection instrument. The cuvette includes a blood sample receptor-inlet; a channel arrangement including at least one test channel for performing a blood clotting time measurement, a sampling channel having at least one surface portion that is hydrophilic, communicating with the blood sample receptor-inlet and the at least one test channel, and a waste channel having at least one surface portion that is hydrophilic, communicating with the sampling channel; and a vent opening communicating with the sampling channel. The sampling channel, the vent opening and the waste channel, coact to automatically draw a requisite volume of a blood sample deposited at the blood receptor-inlet, into the sampling channel. More specifically, air compressed within the blood clot detection instrument, the at least one test channel of the cuvette, and the section of the sampling channel extending beyond the vent opening of the cuvette, coacts with the waste channel to cause a leading edge of the blood sample drawn into the sampling channel from the blood receptor-inlet, to pull back within the sampling channel and uncover an optical sensor in of the blood clot detection instrument. The uncovering of the optical sensor activates a pump module of the blood clot detection instrument, which draws the requisite volume of the blood sample into the at least one test channel.

Cuvette-based apparatus for blood coagulation measurement and testing

An apparatus for measuring blood clotting time includes a blood clot detection instrument and a cuvette for use with the blood clot detection instrument. The cuvette includes a blood sample receptor-inlet; a channel arrangement including at least one test channel for performing a blood clotting time measurement, a sampling channel having at least one surface portion that is hydrophilic, communicating with the blood sample receptor-inlet and the at least one test channel, and a waste channel having at least one surface portion that is hydrophilic, communicating with the sampling channel; and a vent opening communicating with the sampling channel. The sampling channel, the vent opening and the waste channel, coact to automatically draw a requisite volume of a blood sample deposited at the blood receptor-inlet, into the sampling channel.

An apparatus for implementing a skin incision has a torsion spring and a method of assembling the apparatus. The apparatus has a housing having a pair of housing sections, each of the housing section having a base and a plurality of walls. The housing defines an inner space and an exterior. A pivot arm is pivotally mounted to a base of a housing section. The pivot arm is guided between a first position and a second position by a follower in a cam carried by the housing. A torsion spring carried by a spring post is coupled to the arm to exert a spring force on the arm in the first position. The housing has an indentation with a raised level and a lower groove on the base for receiving a portion of the spring post. The opening through the base extends from the lower groove. The spring post has a cylindrical base portion adapted to be received by the indentation in the base and a detent portion. The detent portion has a circular segment detent portion and a turn element accessible from the exterior of the housing. The circular segment detent portion is adapted to engage the raised level of the indentation in the install position and be retained in the lower groove in the loaded position. A trigger mechanism is received in the housing and acts with the pivot arm when activated whereby the arm moves from the first position to the second position due to the spring energy.

Incision device capable of automatic assembly and a method of assembly

A low cost safety lancet device for creating a skin incision. The lancet contains a unitarily formed plastic body, thereby making the lancet device easy to manufacture at a low cost. The lancet device includes a blade beam having a cutting blade disposed at one end for generating an incision in a patient's skin. The blade beam is pivotally coupled within the device, engages a beam keeper arm in a first position and disengages the beam keeper arm in a second position. Upon activation of the device, the blade beam member resiliently deflects in a first direction as the beam keeper arm moves from the first position to the second position thereby causing a buildup of a biasing force in the beam member. When the blade beam disengages the beam keeper arm in the second position, the biasing force built up in the beam member causes the beam member to pivot, thereby accelerating the cutting blade through an aperture in the lancet device to incise the user's skin. The acceleration of the blade beam and cutting blade resiliently deflects the blade beam into a second direction, building up a second biasing force which causes the blade beam to return to a non-deflected position thereby withdrawing the cutting blade from the user's skin and back through the aperture.

Low cost disposable lancet

A portable device for performing coagulation tests on a patient's blood. Blood is first drawn from a patient using a lancet. The blood is then supplied to a disposable cuvette placed within the testing device. The blood is drawn into multiple conduits within the cuvette. Each of the conduits contains a dried or lyophilized activation reagent that is rehydrated by the blood. The blood in each of the conduits is then reciprocally moved across a restricted region until a predetermined degree of coagulation occurs. Since the coagulation time is being monitored in multiple conduits, a representation coagulation time for a given sample can be determined. In at least one of the conduits a normalizing control agent is present. The normalizing control agent counteracts any effects of anticoagulants present in the blood sample, thereby allowing the blood sample to have generally normal coagulation characteristics. The normalized blood is tested simultaneously with the untreated blood to provide a reference value against which the functionality of the test system and the quality of the sample can be judged.

Blood sampling device

An apparatus for implementing a skin incision has an incision blade having at least three facets and at least one sharpened apex. Each of the facets narrows down to one of the apexes. A housing having an exterior surface adapted to be placed flush against the skin and an elongated slot located on the exterior of the surface housing the incision blade. A blade pivoting mechanism located in the housing guides the incision blade through the slot. The blade pivoting mechanism has a first end and second end wherein the first end is pivotally coupled to the housing and the second end supports the incision blade. An actuatable depressing mechanism, located within the housing means, engages and holds the blade pivoting mechanism in a set position, preventing the pivotal movement of the blade pivoting mechanism within the housing. When the depressing mechanism is actuated, the blade pivoting mechanism disengages and transverses the sloped surface, displacing the second end of the blade pivoting mechanism toward the elongated slot, such that the multiple facets of the incision blade emerge from the elongated slot and incise the skin.

Plastic incision blade

A low cost safety lancet device for creating a skin incision. The lancet contains a unitarily formed plastic body, thereby making the lancet device easy to manufacture at a low cost. The lancet device includes a housing having an internal hollow and a blade beam pivotally disposed within the hollow of the housing for generating an incision in a patient's skin. Upon the activation of the device, the blade beam pivots through a predetermined path which causes a blade associated with the blade beam to travel out of an aperture in the housing to incise the patient's skin. The device further includes a trigger for propelling the blade through the path and a cam projection disposed within the housing which cooperates with the trigger to accelerate the trigger through the hollow of the housing thereby causing the blade to accelerate through the aperture of the housing. A portion of the trigger then unavoidably deflects to automatically allow the blade to retract back into the hollow of the casing after incising the patient's skin.

Portable prothrombin time test apparatus and associated method of

A low cost lancet device for creating a skin incision. The lancet contains a unistructurally formed plastic body, thereby making the lancet device easy to manufacture at low cost. The plastic body contains a resilient spring loop that attaches an arm element to an opposing base element. The spring loop is curved, therefore the arm element is retained above the base element by the spring loop. A blade is disposed on the arm element. The blade aligns with a slot in the base element so that when the spring loop is compressed, and the arm element is moved toward the base element, the blade extends through the slot in the base element. A protrusion extends from the base element that obstructs the movement of the arm element toward the base element. As a result, when a force is applied to the arm element, the arm element abuts against the protrusion and applies a bias to the protrusion that acts to displace the protrusion. When a predetermined threshold force is applied to the arm element, the arm element moves past the obstructing protrusion and the arm element rapidly moves toward the base element, compressing the spring loop. As the arm element approaches the base element, the blade on the arm element extends through the slot in the base element and creates the desired incision. Once the applied force is removed from the arm element, the bias of the spring loop moves the arm element away from the base element, thereby retracting the blade back through the slot in the base element.

A self-activated blood drop generator device comprising a casing having an internal hollow and blade assembly disposed within the hollow of the casing for generating an incision in a patient's skin. The device includes a fork-shaped triggering mechanism coupled to the blade assembly for propelling the blade assembly through a predetermined path. A cam arrangement associated with the casing causes the cutting portion of the blade assembly to travel through an arcuate scapel-like path as the cutting portion passes through an aperture in the casing. A retractor arrangement associated with the casing, the blade assembly and the triggering mechanism, are provided for retracting the blade assembly into the hollow of the casing. Also provided is accelerator arrangement associated with the casing and the triggering mechanism for accelerating the triggering mechanism through the hollow of the casing thereby causing the blade assembly to accelerate through the predetermined path. The activation of the device causes the cutting portion of the blade to travel out of the hollow of the casing through the aperture to incise the patient's skin and then retract back through the aperture into the hollow of the casing.

Self activated finger lancet

A portable device for performing coagulation tests on a patient's blood. Blood is first drawn from a patient using a lancet. The blood is then supplied to a disposable cuvette placed within the testing device. The blood is drawn into multiple conduits within the cuvette. Each of the conduits contains a dried or lyophilized activation reagent that is rehydrated by the blood. The blood in each of the conduits is then reciprocally moved across a restricted region until a predetermined device of coagulation occurs. Since the coagulation time is being monitored in multiple conduits, a representation coagulation time for a given sample can be determined. In at least one of the conduits a normalizing control agent is present. The normalizing consol agent counteracts any effects of anticoagulants present in the blood sample, thereby allowing the blood sample to have generally normal coagulation characteristics. The normalized blood is tested simultaneously with the untreated blood to provide a reference value against which the functionality of the test system and the quality of the sample can be judged.

Portable test apparatus and associated method of performing a blood

A blood sampling and transferring device including a disposable auto-pricking lancet and a reservoir integrated together for creating a skin incision and collecting a blood sample therefrom in a one-step operation. The reservoir is preferably funnel shaped with a large opening at one end for receiving the blood sample from the patient, and a small opening at the other end which is small enough to prevent unassisted passage of the collected blood therethrough. The blood sample can then be temporarily stored until such time as the sampling device is engaged with a blood testing device that has an aperture to accommodate the small opening of the reservoir and a pump to draw the blood from the reservoir for testing.

Growing community of inventors

Bridgewater, NJ, United States of America

Anthony F Kuklo, Jr