Koninklijke Philips Corporation N.V.

Medic-aid Limited

Respironics, Inc.

Respironics Respiratory Drug Delivery (uk) Ltd

Profile Respiratory Systems Limited

Profile Drug Delivery Limited

Respironics Respiratory Drug Delivery

Anthony Dyche

Jonathan Stanley Harold Denyer

Jonathan S H Denyer

Ian Thomas Petherbridge

Michael James Robbert Leppard

Ivan Prince

Ian Philip Rabbetts

Jacek Lech Basista

Alphonsus Tarcisius Jozef Maria Schipper

John Stanley Denyer

Ivan Richard Prince

Timothy Spencer

Dirk Ernest Von Hollen

Klaas Jacob Lulofs

Jacob Roger Haartsen

Jonathan Stanley Denyer

Paul Stanley Hensey

Charles David Hillier

Richard Marsden

Ivan R Prince

Jonathan Sh Denyer

A substance delivery module () and apparatus () for delivering a substance in aerosol form are disclosed. The substance delivery module () comprises a substance container (), a piston () and an actuator () configured to engage the substance container () and urge the substance container () onto the piston (), so dispensing the substance into the through passage () of the piston. The actuator () and substance container () are mounted in the substance delivery module () for relative motion, such relative motion bringing the actuator () into engagement with the substance container (). The substance delivery module () may be assembled with an aerosol generator () and an aerosol delivery conduit () to form an apparatus () for delivering a substance in aerosol form. The apparatus () may further comprise a control module ().

Substance delivery module

A substance delivery module and apparatus for delivering substance in aerosol form are disclosed. The substance delivery module includes a plurality of substance containers and a plurality of pistons, with each substance container being mounted in the module for cooperation with a dedicated piston. Another substance delivery module is disclosed that includes a piston defining a delivery axis and a substance container, moveably mounted with respect to the piston. The substance container is moveable along the delivery axis and may, for example, be moved toward and onto the piston. Either of the substance delivery modules may be assembled with an aerosol generator and an aerosol delivery conduit in fluid communication with the aerosol generator to form an apparatus for delivering substance in aerosol form. The apparatus may further include a control module.

Cartridge for substance delivery module

Therapy regimes of a plurality of subjects are remotely monitored and/or managed, wherein the therapy regimes include reception of aerosolized medicament. This enables users such as medical care providers, researchers, clinic administrators, and/or other users to monitor and/or manage the therapy regimes of the plurality of subjects through a centralized access point. This reduces physical requirements of proximity for the users and/or the subjects, alleviates the administrative burden placed on the users to manage and/or monitor individual therapy regimes, and/or provides other enhancements over convention systems.

System and method of remotely monitoring and/or managing the treatment of a plurality of subjects with aerosolized medicament

There is provided a method of monitoring the lung function of a patient, the method comprising determining one or both of an inhalation time and a rest time for a patient that is using a respiratory apparatus, the one or both of an inhalation time and a rest time for the patient being determined from measurements obtained from the respiratory apparatus, wherein the inhalation time is the amount of time for which the patient inhales through the respiratory apparatus, and the rest time is the amount of time between the end of an exhalation and the start of the next inhalation; and analyzing the determined one or both of the inhalation time and rest time to determine an indication of the lung function of the patient.

Method and system for monitoring the lung function of a patient

Therapy regimes of a plurality of subjects are remotely monitored and/or managed, wherein the therapy regimes include reception of aerosolized medicament. This enables users such as medical care providers, researchers, clinic administrators, and/or other users to monitor and/or manage the therapy regimes of the plurality of subjects through a centralized access point. This reduces physical requirements of proximity for the users and/or the subjects, alleviates the administrative the burden placed on the users to manage and/or monitor individual therapy regimes, and/or provides other enhancements over convention systems.

A monitoring device includes a housing that is constructed and arranged to be removably attached to a drug delivery device for an inhaled drug. A color detector is operatively associated with the housing and constructed and arranged to detect an identifying color of at least a portion of the drug delivery device when the housing is attached to the drug delivery device and to output color information for use by a processor to, based on the detected color, identify information about the inhaled drug.

Color identification for drug delivery system

A nebulizer comprises a head detachably coupled to a body. The head comprises a nebulizer, an air channel and a flow sensor. A nebulized liquid is released in an air channel that ends in a mouth piece through which a user inhales and exhales. The inhaling and exhaling causes a flow in the air channel which is detected with the flow sensor. The nebulizer is controlled by a controller included in the body.

Nebulizer

A nebulizer () comprises one or more removable components (), for example a mesh assembly (), mouthpiece, plunger assembly () and medication chamber (), each having an associated data carrier (). The data carrier () can be used to store information indicating the type of removable component () that is fitted to the nebulizer (). A removable component () may be from a set of such removable components. For example, a mouthpiece () fitted to the nebulizer () may be from a set of mouthpieces having different flow rates. The data carrier () may also be used to control operation of the nebulizer (). A data carrier () attached to a mesh () may be used to prevent the nebulizer () from being used when the mesh () has been used a predetermined number of times.

Drug delivery apparatus and method

There is provided a method of determining whether a first type of liquid is being used in a nebulizer, the method comprising obtaining a measurement of the time taken by the nebulizer to nebulize a specified volume of liquid that was held therein, comparing the time taken to nebulize the specified volume of liquid to an estimated value for the time required to nebulize the same volume of the first type of liquid, and determining whether the liquid nebulized by the nebulizer was the first type of liquid based on the comparison.

Apparatus for use with a nebulizer and a method of operating a nebulizer

A medication delivery apparatus () includes a reservoir for holding a liquid medication and a metering device () coupled to the reservoir for supplying a dose of the liquid medication to the reservoir. The metering device includes an upper chamber, a lower chamber coupled to the upper chamber, a piston selectively moveable within the upper chamber and the lower chamber and a valve providing selective fluid communication between the lower chamber and the reservoir in response to movement of the piston.

Medication delivery apparatus including a medication metering system

A server is configured to be communicatively linked with drug delivery devices used by a plurality of different subjects to receive aerosolized medicament as part of a therapy regime. The server provides a user with a user interface that enables the user to access therapy information related to the therapy of a plurality of different subjects. This may facilitate the monitoring of therapy received by the plurality of subjects.

System and method for enabling therapeutic delivery of aerosolized medicament to a plurality of subjects to be monitored

A drug package comprising a plurality of drug vials containing drugs for delivery to a patient in a drug delivery device; and a data carrier including drug treatment information for use by the drug delivery apparatus.

Controlling drug delivery apparatus

A drug delivery apparatus of the type which releases a drug in aerosolized form into the inhaled airstream of a person, programmed to release the drug in a pulse which ends a pre-set time before the person is expected to stop inhaling. In doing so, a minimum residence time within the lungs is created, and drug treatment time can be reduced. A corresponding method of controlling a drug delivery apparatus comprises the step of controlling the apparatus to release the drug in aerosolized form into the inhaled airstream of a person in a pulse which ends a pre-set time before the person is expected to stop inhaling.

Inhalation method and apparatus

A nebulizer includes nebulization device for nebulizing a substance and a reservoir having a metering chamber arranged so as to feed a substance to be nebulized to the nebulization device and a second chamber arranged to hold and retain any of this substance in excess of the volume held in the metering chamber.

Nebulizer metering chamber

An aerosol drug delivery apparatus is provided. The apparatus may include a reservoir constructed to contain a predetermined dose of a liquid drug, an aerosol generator in communication with the reservoir, and a power source arranged to deliver power to the aerosol generator in order to produce an aerosolized form of the dose that can be administered to a patient. The apparatus may maintain consistent aerosol drug delivery treatments, for example, by way of a breath measuring mechanism that monitors the patient's breathing pattern during the administration of the dose and a controller configured to vary the power level at which the power source during the administration of the dose based on the monitored breathing pattern.

Growing community of inventors

Hayling Island, United Kingdom

Anthony Dyche