Commonwealth Scientific and Industrial Research Organisation

Anthony Brian Clayton

Gordon Francis Meijs

Timothy Charles Hughes

Peter Agapitos Kambouris

A method of preparing intraocular lenses in situ is disclosed. The method involves the injection of an unsaturated macromonomer of Formula I:  The macromonomer is then polymerized to give a polymer suitable for use in an intraocular lens.

Biomedical compositions

A method of preparing intraocular lenses in situ is disclosed. The method involves the injection of an unsaturated macromonomer of the formula The macromonomer is then polymerized to give a polymer having an E modulus in the range 0.5-5 kPa.

Biomedical composition

A hydrophilic ethylenically unsaturated macromonomer is disclosed that is prepared by the addition polymerization of addition polymerizable monomers that include monomers that have hydroxyl or amino functional groups, some of which may be subsequently reacted to provide (meth)acryl ethylenic unsaturation. The macromonomers may be used to form intraocular lenses in situ by polymerization of the macromonomers, and thus treat presbyopia.

Hydrophilic biomedical compositions

A hydrophilic ethylenically unsaturated macromonomer is disclosed that is prepared by the addition polymerization of addition polymerizable monomers that include monomers that have hydroxyl or amino functional groups, some of which may be subsequently reacted to provide (meth)acryl ethylenic unsaturation. The macromonomers may be used to form intraocular lenses in situ by polymerization of the macromonomers.

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Oakleigh, Australia

Anthony Brian Clayton