Tcp Reliable, Inc.

Haarmann, Klaus H.

Barakat, Maurice

Alleva, Anthony

Thibault, Louis

Lapointe, Serghe

Tremblay, Mario

Beausejour, Annie

Klaus H. Haarmann

Serghe Lapointe

Maurice Barakat

Anthony Alleva

Mario Tremblay

Annie Beausejour

Louis Thibault

Klaus H Haarmann

Eric Mirabel

Thomas-Laurent Bringas

Thomas-Laurent Bingas

Annie Beauséjour

A new blood unit cooling system was designed to cool blood rapidly to about 22&#xb0; C. and maintain it at about that temperature, even in ambient temperature extremes, for several hours. The system incorporating a preferred eutectic solution including 98% 1-dodecanol 1.5% myristyl alcohol and 0.5% 1-decanol (having a melting point of about 23&#xb0; C.) contained in a sealed flexible polymer layer, was used to cool whole blood-filled bags. The preferred design uses inner and outer containers, each made of transparent polyethylene sheets, where the inner compartments are filled with the solution and sealed, and then placed into each compartment in an outer container, wherein two compartments in the outer container are separated by a flattened and sealed portion of the polyethylene.

Fabricating a phase change blood cooling system

Disclosed is a process of selecting of a container and temperature-control system, such that biological products (including blood) requiring maintenance within a specified range of temperatures are so maintained during shipment. The process requires a prediction of the maximum period of shipment, and the predicted ambient temperature ranges and time of exposure thereto for the system during the period of shipment. With that information, a system of container(s) with temperature-control agents including dry ice, ice, frozen gel packs or a phase change material, is selected.

Selecting packaging and coolant systems for shipment of biological products

A new blood unit cooling system was designed to cool blood rapidly to about 22&#xb0; C. and maintain it at about that temperature, even in ambient temperature extremes, for several hours. The system incorporating a preferred eutectic solution including 98% 1-dodecanol, 1.5% myristyl alcohol and 0.5% 1-decanol (having, a melting point of about 23&#xb0; C.) contained in a sealed flexible polymer layer, was used to cool whole blood-filled bags. The preferred design uses inner and outer containers, each made of transparent polyethylene sheets, where the inner compartments are filled with the solution and sealed, and then placed into each compartment in an outer container, wherein two compartments in the outer container are separated by a flattened and sealed portion of the polyethylene.

Fabricating a flexible rapid blood cooling system

A new blood unit cooling system was designed to cool blood rapidly to about 22&#xb0; C. and maintain it at about that temperature, even in ambient temperature extremes, for several hours. The system incorporating a preferred eutectic solution including 98% 1-dodecanol, 1.5% myristyl alcohol and 0.5% 1-decanol (having a melting point of about 23&#xb0; C.) contained in a sealed flexible polymer layer, was used to cool whole blood-filled bags. The preferred design used double-layered transparent polyethylene, with two sealed compartments filled with the solution, separated by a flattened and sealed portion between them. One of the two sealed compartments contacts one side of the blood bag and the other compartment is folded over to contact the other side of the blood bag. The transparent compartments allows an operator to verify at any time whether the solution is in a solid state, and the flexibility of the compartments eases the proper positioning of them around a blood bag.

Rapid cooling to and maintaining of whole blood at 20 to 24C for processing

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Keansburg, NJ, United States of America

Anthony Alleva