Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

Antal Gajari

Lajos T Nagy

Istvan Szekely

Eva Somfai

Laszlo Pap

Bela Bertok

Sandor Botar

Sandor Zoltan

Gyorgy Hidasi

Agnes Hegedus

Tamas Szabolcsi

Erzsebet Radvany

Rudolf Soos

Ruldof Soos

A process is disclosed for preparing a synergistic, crystalline product consisting of solely enantiomer pair 1RCisS and 1SCisR and enantiomer pair 1RTransS and 1STransR of cypermethrin in a 3:7 to 5:5 crystalline mixture, which comprises the steps of: (a) epimerizing an oily melt or a saturated solution of enantiomer pair 1RCisS and 1SCisR and enantiomer pair 1RTransS and 1STransR in a ratio other than 3:7 to 5:5, or a mixture of enantiomer pair 1RCisS and 1SCisR, enantiomer pair 1RTransS and 1STransR together with enantiomer pair 1RCisR and 1SCisS and enantiomer pair 1RTransR and 1STransS, said saturated solution including a protic or apolar, aprotic inert organic solvent by treating said oily melt or saturated solution with an organic or inorganic base at a temperature of -15.degree. C. to 30.degree. C. to precipitate crystals consisting solely of the 1RCisS and 1SCisR and the 1RTransS and 1RTransR enantiomer pairs in a 3:7 to 5:5 weight ratio; (b) isolating the precipitated crystals consisting solely of the enantiomer pairs 1RCisS and 1SCisR and 1RTransS and 1STransR at -10.degree. to 30.degree. C., optionally after inoculating the reaction mixture with a seeding crystal consisting of a mixture of the enantiomer pairs 1RCisS and 1SCisR and 1RTransS and 1STransR at a weight ratio of 3:7 to 5:5 before crystallization; and (c) repeating any of the above steps, if necessary.

Insecticidal composition comprising more than one active ingredient

According to the present invention there is provided a synergistic insecticidal composition containing more than one active ingredients and being harmless to environment characterized by comprising in an amount of from 0.001 to 99% by weight a synthetic pyrethroid of the Formula /I/ ##STR1## namely substantially only the 1RtransS and 1StransR entantiomer-pair /Ib/ out from the possible eight isomers--optionally in admixture with an amount of up to 100% by weight of one or more activator/s/ and auxiliary agent/s/, particularly antioxidants, stabilizing agents, wetting agents, emulsifying agents, dispersing agents, antifoam agents, diluents and/or fillers. The enantiomer-pair Ib consisting of the 1RtransS and 1StransR isomers is new and the invention also relates to the said new enantiomer-pair and a process for the preparation thereof. The advantage of the insecticidal composition of the present invention is that it is less toxical towards warm-blooded animals and useful parasites and is therefore much less harmful to the environment.

According to the present invention there is provided an insecticidal composition containing more than one active ingredients which comprises as active ingredient in an amount of 0.001-99% by weight a synthetic pyrethroid of the general Formula I ##STR1## wherein X stands for chlorine or bromine--namely out of the eight possible isomers at least 95% of a 55:45-25:75 mixture of the enantiomer-pairs Ia:Ib, wherein Ia is 1RcisS+1ScisR and Ib is 1RtransS++1StransR--if desired, in admixture with an activator and/or with an amount of up to 100% of an auxiliary agent, preferably an antioxidant, stabilizer, wetting agent, emulsifying agent, dispersing agent, antifoam agent, diluent, carrier, and/or filler. The advantage of the insecticidal composition of the present invention is that it is less toxical towards warm-blooded animals and useful parasites and is therefore much less harmful to the environment.

Pyrethroidal composition comprising more than one active ingredients

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Budapest, Hungary

Antal Gajari