Torrent Pharmaceuticals Limited

Anoop Mathur

Jaya Abraham

Chaitanya Dutt

Shailesh Deshpande

Vivek Mishra

Jignesh Kotecha

Anita Chaudhari

Amit Kesarwani

Sachin Latad

Manish Patel

Shital Kumar Zambad

Rameshchandra Gupta

Ramesh Chandra Gupta

This invention relates to pharmaceutical formulations comprising 1-(2-thien-2'-yl-2-oxo-ethyl)-3-(methanesulfonyl hydrazine carbonyl) pyridinium, its pharmaceutically acceptable salts, salt-cocrystals and co-crystals, particularly 1-(2-thien-2&#x2032;-yl-2-oxo-ethyl)-3-5(methanesulfonyl hydrazine carbonyl) pyridinium chloride. The formulations are suitable for oral administration and also comprise a permeability enhancer or a suitable base or a mixture thereof. The formulations of this invention are for treating diseases associated with advanced glycation end products.

Pharmaceutical formulations

The present invention relates to novel pyridinium compounds, their isomers, steroisomers, atropisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses process for preparing novel compounds and pharmaceutical composition of said compounds. The invention further relates to the use of the above mentioned compounds for the preparation of medicament for use as pharmaceuticals.

Pyridinium compounds

Growing community of inventors

Gandhinagar, India

Anoop Mathur