Orion Corporation

Anniina Vesalainen

Gerd Wohlfahrt

Olli Törmäkangas

Arja Karjalainen

Harri Salo

Patrik Holm

Sirpa Rasku

Iisa Höglund

Pia Koivikko

Terhi Heikkinen

Anu Moilanen

Pia Knuuttila

Rathna Durga Ramasubramanian

Pranab Kumar Patra

Arputharaj Ebenezer Martin

Olli Toermaekangas

Iisa Hoeglund

Olli Tormakangas

Lisa HÖGLUND

The present disclosure relates to compounds of formula (I), and pharmaceutically acceptable salts thereof. The present disclosure also relates to compositions and methods of treating comprising compounds of formula (I), and pharmaceutically acceptable salts thereof. 

Androgen receptor modulating compounds

The present disclosure relates to compounds of formula (I), and pharmaceutically acceptable salts thereof. The present disclosure also relates to compositions and methods of treating comprising compounds of formula (I), and pharmaceutically acceptable salts thereof.

Compounds of formula (I) or (II) wherein R, R, R, R, R, R', R, R&#x2032;, A and B are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds possess utility as tissue-selective androgen receptor modulators (SARM) and are useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.

Androgen receptor modulating carboxamides

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Paimio, Finland

Anniina Vesalainen