Kuros Biosurgery Ag

Annemie Rehor

Simona Cerritelli

Peter Lutz

Methods for making biomaterials for use as a tissue sealant, kits containing precursors for forming the biomaterials, and the resulting biomaterials are described herein. The biomaterials are formed from a composition comprising at least a first and a second precursor molecule, wherein: The precursors are selected based on the desired properties of the biomaterial. Optionally, the biomaterials contain additives, such as thixotropic agents, radiopaque agents, or bioactive agents. In the preferred embodiment, the biomaterials are used to reduce, inhibit, or contain loss of a biological fluid or gas in a patient.

Polymeric tissue sealant

The application relates to a dispensing device () containing at least one chamber (') for receiving a fluid (B, B&#x2032;), a plunger unit () including at least one piston (&#x2032;), locking mechanism and counter-locking mechanism as well as a catching mechanism and counter-catching mechanism. The locking mechanism and the counter-locking mechanism can be brought into a locking position (L), in which a movement of the plunger unit () in one or both directions is substantially prevented. The catching mechanism and the counter-catching mechanism can be brought into an engagement position (E), in which the locking mechanism and the counter-locking mechanism cannot be brought into the locking position (L). Furthermore, the application relates to a kit () containing the dispensing device () and to a method of operating the device () or kit ().

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Winterthur, Switzerland

Annemie Rehor