Sanofi-a Ventis Deutschland Gmbh

Aventis Pharma Deutschland, Gmbh

Aventis Pharmaceuticals Inc.

Sanofi

Anne Minnich

Robert D Groneberg

Daniel Gerard McGarry

Michael F Kelley

Michael R Angelastro

Richard F Labaudiniere

Gerard M McGeehan

Haifeng Eishingdrelo

Theresa Kuntzweiler

Mark A Bobko

Litao Zhang

Zaid Jayyosi

Hans-Jochen Lang

Ercole Rao

Robert L Morris

Danxi Li

Thomas Caulfield

Otmane Boussif

Sophie Carayon

Amirtha Naadimuthu

Stephan Henke

Florent C Bender

Brian N Swanson

Thomas J Caulfield

Lei Tang

Haixin Yu

Mark Bobko

Uses of a dual V region antibody-like protein or a fragment of a dual V region antibody-like region.

Uses of a dual V region antibody-like protein

The use of diaryl acid derivatives of formula (I)or pharmaceutically acceptable salts, N-oxides, hydrates or solvates thereof, wherein the variables shown are defined in the disclosure, and their pharmaceutical compositions as PPAR ligand receptor binders. The PPAR ligand receptor binders of this invention are useful as agonists or antagonists of the PPAR receptor.

Therapeutic uses of di-aryl acid derivatives

Host cells expressing HM74 were used to obtain oxydecalin-like molecules with agonist activity having the following structure: 

Oxydecahydronaphthalene modulators of HM74

Host cells expressing HM74 were used to obtain furosemide-like molecules with agonist activity having the following structure formula: 

Furosemide modulators of HM74

The use of triaryl acid derivatives of formula (I)and their pharmaceutical compositions as PPAR ligand receptor binders. The PPAR ligand receptor binders of this invention are useful as agonists or antagonists of the PPAR receptor.

Therapeutic uses of tri-aryl acid derivatives

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Flemington, NJ, United States of America

Anne Minnich