Centre National De La Recherche Scientifique

Institut National De La Sante Et De La Recherche Medicale

Université Paris Descartes

Anne-Laure Turcot-Dubois

Marc Bonneville

Didier Dubreuil

Muriel Pipelier

Laurent Micouin

Thomas Lecourt

Vivien Lacone

Jacques Lependu

The invention relates to &#x3b1;-galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods. It also relates to pharmaceutical compositions containing the &#x3b1;-galactoceramide analogs. The methods of manufacture of the invention involve the use of unsaturated intermediate compounds which enable to synthesize &#x3b1;-galactoceramide analogs by a mere metathesis reaction. The &#x3b1;-galactoceramide analogs of the invention are useful as active ingredients of pharmaceutical compositions, particularly in pharmaceutical compositions having anti-cancerous properties.

&#x3b1;-galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods, and pharmaceutical compositions containing them

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Nornaison, France

Anne-Laure Turcot-Dubois