Nant Holdingsip, LLC

Chan Soon-shiong Nanthealth Foundation

Anne-Laure LeNy

Patrick Soon-Shiong

Kayvan R Niazi

Shahrooz Rabizadeh

Oleksandr V Buzko

Justin Golovato

Antiviral compositions and methods are contemplated that are especially effective in the treatment and prevention of influenza A viruses. Also presented are cellular assays to identify small molecule compounds having antiviral properties, particularly as it relates to detection of influenza A RNA-dependent RNA polymerase activity in a mammalian cell independent of other influenza A components. Preferred assays allow for identification of viral replication inhibitors that do not disrupt normal cellular activity.

Small molecule inhibitors of influenza A RNA-dependent RNA polymerase

Compositions and methods are contemplated for treatment of a wound, and especially a sterile or TLR/NOD ligand-poor wound in which contemporaneous administration of a Ca-flux agonist (CFA) and a pattern recognition receptor (PRR) ligand improves wound healing.

Compositions and methods of improved wound healing

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South Pasadena, CA, United States of America

Anne-Laure LeNy